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The San Francisco 49ers vs Las Vegas Raiders game is set to be a thrilling encounter in the 2025 NFL season. Our prediction model, which has a strong track record, suggests a close match with the 49ers slightly edging out the Raiders. We predict a final score of 27-24 in favor of the 49ers. The moneyline pick favors the 49ers, with a coverage percentage of 57.7% in similar past encounters. Visit our NFL picks page for more insights.
Our prediction model has been profitable in the last 10 games, winning 6 of them on the American Totals market. This game offers a high EV on the moneyline, making it an attractive option for bettors today.
Seattle - -3½ -110BetOnline | |||||||
![]() L.A. Rams - -3 -120Bovada | |||||||
Jacksonville - -7½ -101Bet105 | |||||||
![]() Cincinnati - -3½ -102Bet105 | |||||||
![]() Indianapolis - +3½ -110BetOnline | |||||||
![]() Pittsburgh - -2½ -122Bet105 | |||||||
![]() Houston - +1½ -120Bovada | |||||||
Carolina - +2½ -102Bet105 | |||||||
![]() Tennessee - -2½ -110Bookmaker | |||||||
Detroit - -7 -105Bet105 | |||||||
![]() L.A. Chargers - -10 -115Bookmaker | |||||||
![]() Las Vegas - -3 -120BetOnline | |||||||
Philadelphia - -4 -103Bet105 | |||||||
Minnesota - +1½ -115Bovada | |||||||
![]() N.Y. Giants - +3 -110MyBookie | |||||||
![]() Kansas City - -2½ -110MyBookie |