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Get ready for an electrifying NFL showdown as the New Orleans Saints take on the Seattle Seahawks on September 21, 2025, at Lumen Field in Seattle, WA. This game promises to be a thrilling encounter with both teams eager to secure a win in Week 3 of the 2025-26 NFL season. With the Seahawks playing at home, they are slight favorites, boasting a point spread of -7 -113 according to Caesars. Meanwhile, the Saints are looking to upset with a spread of +7 -107. These odds reflect a tightly contested game.
For those looking to place bets, the moneyline shows the Seahawks as favorites at -390, while the Saints are at +305, both offered by Caesars. The over/under is set at 41.5, with both options priced at -110. Bettors should consider the Seahawks' strong home-field advantage and the Saints' ambitions to turn the tides. Catch the action live on CBS, and for more detailed odds, visit our NFL odds page.
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