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Get ready for a thrilling NFL showdown as the Seattle Seahawks take on the Pittsburgh Steelers at Acrisure Stadium in Pittsburgh, PA, on September 14, 2025. This clash, part of the 2025-26 NFL season's Week 2, promises to be a must-watch, with both teams eager to make their mark early in the season. Broadcasted on FOX, fans can catch every moment of the action. The current point spread has the Steelers favored by 3 points, with odds at -115, while the Seahawks stand at +3 with -105 odds. The opening odds showed a similar spread, indicating a consistent expectation among sportsbooks that the Steelers have the edge. For those looking to make informed bets, understanding the betting lines and point spread can be crucial. The Steelers, playing at home, are expected to leverage their fanbase and familiarity with Acrisure Stadium to their advantage. Meanwhile, the Seahawks are determined to upset the odds and secure a victory on the road. The over/under is set at 40.5, providing an additional angle for bettors to consider. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook. Check out the latest odds on our NFL odds page.