- Puck Line
- Money
- Total
- Merged
Personalize your notifications and get updates on the teams, players or events you care about most.
FINAL
Apr 21, 2026 7:30 PM EDTGame 2: BUF Wins Series 4-2
BOS 4 vs BUF 2
BUF
-156o6 (-111)
ESPN, NESN, MSG-B, TVAS2, TVAS, SN360BETCAST
PLAYS
MATCHUP
PREDICTION
ODDS
PLAYER PROPS
GAME PROPS
INJURIES
CHAT
Event NotificationsStay on top of the action with alerts for game start, scoring, odds updates, predictions and more.
Don't show me this again
Boston Bruins vs Buffalo Sabres Picks
Updated:Apr 21, 2026 2:18 AM EDT
The Boston Bruins face the Buffalo Sabres today, April 21, 2026, at KeyBank Center in Buffalo, NY, in an NHL regular-season matchup broadcasted on ESPN, NESN, MSG-B, TVAS2, TVAS, and SN360. Buffalo leads the series 1-0 after a 4-3 win on April 19. Our picks predict a 4-3 victory for Buffalo with a +5.7% EV and a 66.8% hit rate on the 2-way market including overtime and penalties. Buffalo's power play and penalty kill efficiencies outpace Boston's, suggesting a strategic edge. Our model has been profitable in the last 10 NHL games, especially on the 2-way market, providing valuable betting tips. For in-depth analysis, visit our NHL picks page NHL Picks and Predictions.
UPCOMING GAME PREDICTION
Puck Line
Money
Total
BUFMoney
CONSENSUS LINE
-159
PROJECTION
BUF (4) - BOS (3)
COVER PROBABILITY
EXPECTED VALUE
+6.5%
BET RATING
SEASON COVER %
51/83
61%
NHL
Money
Game
- Game
- 1P
- 2P
- 3P
NHLMon 05/25
 Montreal 56-41-167% +125Bet105 | |||||||
 Vegas 50-4760% +105Heritage |
Download the app© OddsTrader 2026 All Rights Reserved
The content on this site is for entertainment purposes only. OddsTrader makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. Please be aware of and respect the laws regarding sports betting for your jurisdiction as they vary from state to state. OddsTrader does not target underaged persons. Using this information to contravene any law or statute is prohibited. This site contains commercial content, and OddsTrader may be compensated for the links provided on this site.Disclosure.
OddsTrader no longer operates under any U.S. license, including Pennsylvania.
Seek help with a gambling addiction at 1-800-Gambler.