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The upcoming NHL matchup features the Buffalo Sabres vs Boston Bruins on April 28, 2026, at KeyBank Center in Buffalo, NY. Broadcasted on networks including TNT, NESN, and Sportsnet, this game is pivotal as Buffalo leads the series 3-1. Our picks predict a 4-3 victory for Buffalo, driven by their superior powerplay and penalty kill percentages compared to Boston. With a 68.1% hit rate and positive 6.3% EV in recent 2way markets, our betting tips reflect a strong confidence in Buffalo maintaining momentum. Explore more detailed NHL picks and predictions to inform your betting strategy.