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FINAL
Nov 21, 2025 7:00 PM EST
CHI 3 vs BUF 9
BUF
-171o6½ (-101)
MSG-B, ESPN+, CHSNBETCAST
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PLAYER PROPS
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Chicago Blackhawks vs Buffalo Sabres Picks
Updated:Nov 21, 2025 1:13 AM EST
The upcoming NHL game on November 21, 2025, features the Chicago Blackhawks vs Buffalo Sabres at KeyBank Center in Buffalo, NY. This matchup is set to be an exciting contest in the 2025-26 NHL season, with the game broadcasted on MSG-B, ESPN+, and CHSN. Our picks for this game favor the Buffalo Sabres with a predicted score of 4 to 3 against the Blackhawks, including overtime and penalties. Our prediction model has shown a solid track record recently, winning 6 out of the last 10 games on the 2way market, which includes overtime and penalties, demonstrating a positive hit rate and EV that bettors can trust.
When comparing the teams, Buffalo has a slightly higher powerplay percentage and penalty kill percentage than Chicago, which could be crucial in tight game scenarios. Chicago, however, holds a competitive edge in 5-on-5 play, making this a balanced and tactical game. Understanding these stats can help bettors make smarter decisions on their bets and parlays, especially when considering the spread and moneyline options. For those looking to dive deeper into NHL betting strategies, check out our comprehensive NHL picks page for more detailed insights and predictions.
Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. The best odds available today for Buffalo are +12.4% EV at SugarHouse and for Chicago 9.7% EV at SugarHouse.
UPCOMING GAME PREDICTION
Puck Line
Money
Total
CHIMoney
CONSENSUS LINE
150
PROJECTION
CHI (3) - BUF (4)
COVER PROBABILITY
EXPECTED VALUE
+5.8%
BET RATING
SEASON COVER %
10/20
50%
NHL
Money
Game
- Game
- 1P
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- 3P
NHLWed 04/22
 Philadelphia 45-3975% -110BetOnline | |||||||
 Minnesota 47-3782% -122BetOnline | |||||||
 Edmonton 42-41100% -178Bet105 | |||||||
 Boston 44-38-2100% -106Heritage | |||||||
 Ottawa 44-40- -119Heritage | |||||||
 Los Angeles 34-49-1- +138Bet105 | |||||||
 Montreal 48-35-1- +103Heritage | |||||||
 Utah 44-40- +102Bet105 |
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