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The upcoming NHL game on April 7, 2026, features the Colorado Avalanche facing the St. Louis Blues at Enterprise Center in St. Louis, MO. Broadcasted on ESPN+ and FDSMw, this matchup offers intriguing betting opportunities. Our picks and predictions favor the Blues with a predicted score of 5 to 3. St. Louis holds a slight edge in powerplay efficiency (51.0% vs. 49.0%) and a positive EV of 8.6%, while Colorado shows a negative EV of -11.0%. The Blues' penalty kill and 5-on-5 percentages suggest a solid defensive play, influencing our recommended bets. Our prediction model has been profitable in recent games, boasting a high EV and hit rate in 2way markets. For more detailed analysis, visit our NHL picks page NHL Picks and Predictions.