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Louisville Cardinals vs Tennessee Volunteers Picks
Updated:Dec 15, 2025 1:17 AM EST
The upcoming NCAAB game on December 16, 2025, between the Louisville Cardinals and Tennessee Volunteers promises to be an exciting showdown at Thompson-Boling Arena in Knoxville, TN. This game is a must-watch for college basketball fans and bettors alike, airing on ESPN. Our expert picks and betting tips are designed to give you an edge in this thrilling contest.
Our prediction model favors the Tennessee Volunteers to win with a predicted score of 75-68, including a moneyline pick on Tennessee. The Volunteers have been solid in recent games, and our model has demonstrated a profitable track record, winning 6 out of the last 10 games with high EV and a strong hit rate on the 2-way market. This consistent performance helps bettors make informed decisions and maximize their returns.
Louisville and Tennessee have a storied rivalry, and this game at Thompson-Boling Arena will be no different. With top-notch analysis and up-to-date stats, our picks page offers all the insights you need to place smart bets. For more comprehensive NCAAB predictions, check out our NCAAB picks and predictions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
NCAAB
Live college basketball odds are always available at OddsTrader. You can keep up with your favorite teams or consider using our stats-driven NCAAB computer picks to help you make smarter wagers. Betting action intensifies during March Madness, making it crucial to track odds and betting lines in real time. New bettors can read on to learn more about NCAAB odds.
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NCAAB Mon 12/15
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 Virginia Commonwealth 6-4- -30½ -120FanDuel | |||||||
 Southeastern Louisiana 4-6- -4½ -110Caesars | |||||||
 Gardner-Webb 1-11- +10 -110Caesars | |||||||
 South Dakota State 7-5100% +4½ -106FanDuel | |||||||
 Alabama A&M 5-4- +2 -110Caesars | |||||||
 Houston Christian 5-5- +12½ -105BetMGM | |||||||
 TCU 6-3- -17½ -110FanDuel | |||||||
 #20Tennessee 7-3- +1 -130SBK |
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