Nov 15, 2025 3:30 PM EST

Week 12

#19 Virginia

5-4

Duke

DUKE

-4½ (-110)o58½ (-115)

ESPN2, 209, ESPN Networks

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Virginia Cavaliers vs Duke Blue Devils Picks

Updated:Nov 14, 2025 4:05 AM EST

The upcoming Saturday football clash on November 15, 2025, between the Virginia Cavaliers and Duke Blue Devils at Brooks Field at Wallace Wade Stadium in Durham, NC is setting the stage for an exciting NCAAF regular season Week 12 showdown. The game will be broadcast on ESPN2, making it accessible to fans and bettors nationwide.

Our expert picks favor the Duke Blue Devils with a predicted score of 33 to 27 over the Virginia Cavaliers, with Duke expected to cover a -4.5 point spread. The predicted total score is 59.5, slightly over the line of 58.5, which aligns well with our profitable American Total market that has shown a strong hit rate recently. This market has been particularly successful, boasting a coverage percentage of 52.8% and an EV of 0.5%, providing bettors with valuable betting tips for making smart wagering decisions.

While Virginia has had mixed results in recent games, Duke's performance has been solid, especially in point spread markets. Our prediction model has been profitable in the last 10 games, winning in key markets such as point spread and totals, which can help bettors make informed bets for this game. For detailed NCAAF picks and predictions, check out our comprehensive NCAAF picks and predictions.

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NCAAF

ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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This Week

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NCAAF Fri 11/14

Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/147:30 PM Clemson 4-5 71% +2½ -105FanDuel
#20Louisville 7-2 29% -1½ -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/149:00 PM Minnesota 6-3 66% +25½ -110BetRivers
#8Oregon 8-1 34% -24½ -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1512:00 PM Air Force 3-6 78% +7½ -110Caesars
Connecticut 7-3 22% -7½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1512:00 PM UTSA 4-5 0% -17 -105Caesars
Charlotte 1-8 100% +18½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1512:00 PM Arizona 6-3 82% +6½ -112Caesars
#25Cincinnati 7-2 18% -6 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1512:00 PM #24South Florida 7-2 77% -10 -110Caesars
Navy 7-2 23% +10½ -114BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1512:00 PM Wisconsin 3-6 84% +29½ -110Bet365
#2Indiana 10-0 16% -29 -112Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1512:00 PM #9Notre Dame 7-2 30% -12½ -105FanDuel
#22Pittsburgh 7-2 70% +12½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1512:00 PM Eastern Michigan 3-7 15% -2½ -110Bet365
Ball State 4-5 85% +2½ -106Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1512:00 PM Kansas State 4-5 25% -19½ -110Caesars
Oklahoma State 1-8 75% +20 -117SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1512:00 PM South Carolina 3-6 28% +18½ -110BetRivers
#3Texas A&M 9-0 72% -17½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1512:00 PM #18Michigan 7-2 55% -10½ -106FanDuel
Northwestern 5-4 45% +11½ -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1512:45 PM Arkansas 2-7 83% +5½ -110Bet365
LSU 5-4 17% -5 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/151:00 PM Oregon State 2-8 60% -2 -108Caesars
Tulsa 2-7 40% +2½ -106FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/151:00 PM West Virginia 4-6 92% +11½ -110Caesars
Arizona State 6-3 8% -11 -114SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/151:30 PM Tennessee Tech 10-0 - +21½ -110Bet365
Kentucky 4-5 - -21½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/152:00 PM Marshall 4-5 24% -7½ -110Caesars
Georgia State 1-8 76% +8 -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/152:00 PM North Texas 8-1 22% -17½ -112Caesars
UAB 3-6 78% +18½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:00 PM Colorado State 2-7 83% +14½ -110Bet365
New Mexico 6-3 17% -14 -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:00 PM UTEP 2-7 100% +5½ -115BetMGM
Missouri State 6-3 0% -4½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM Appalachian State 4-5 30% +21½ -120FanDuel
James Madison 8-1 70% -21 -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM #16Georgia Tech 8-1 51% -16½ -109Caesars
Boston College 1-9 49% +17 -117SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM #19Virginia 8-2 51% +4½ -110Caesars
Duke 5-4 49% -4½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM North Carolina State 5-4 94% +15½ -110BetMGM
#15Miami (FL) 7-2 6% -14½ -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM Penn State 3-6 23% -7 -113Caesars
Michigan State 3-6 77% +7½ -114FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM #11Oklahoma 7-2 88% +6 -105Caesars
#4Alabama 8-1 12% -5½ -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM Texas State 3-6 63% +3½ -124FanDuel
Southern Miss 7-2 37% -3 -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM UCF 4-5 13% +24 -112SugarHouse
#6Texas Tech 9-1 87% -23½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM South Alabama 2-7 33% -4 -115Bet365
Louisiana-Monroe 3-6 67% +4½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM Maryland 4-5 90% +16 -110Bet365
Illinois 6-3 10% -15 -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM #21Iowa 6-3 76% +6½ -105FanDuel
#17USC 7-2 24% -6 -117SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM Middle Tennessee 1-8 100% +13½ -105BetMGM
Western Kentucky 7-2 0% -13 -121SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/153:30 PM San Jose State 3-6 8% -8½ -110FanDuel
Nevada 1-8 92% +9½ +102Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/154:00 PM Memphis 8-2 27% +3 -112Caesars
East Carolina 6-3 73% -2½ -120BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/154:00 PM Florida Atlantic 4-5 100% +17½ -110Caesars
Tulane 7-2 0% -17½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/154:15 PM New Mexico State 3-6 99% +40½ -110Caesars
#23Tennessee 6-3 1% -39½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/154:30 PM North Carolina 4-5 58% +6½ -115FanDuel
Wake Forest 6-3 42% -5½ -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/155:00 PM Liberty 4-5 25% -2½ -110Bet365
Florida International 4-5 75% +3 -118BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/156:00 PM Coastal Carolina 6-3 60% +3½ -110FanDuel
Georgia Southern 4-5 40% -3 -114Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/157:00 PM Delaware 5-4 15% -9½ -122FanDuel
Sam Houston State 1-8 85% +10½ -118SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/157:00 PM #13Utah 7-2 18% -7½ -110FanDuel
Baylor 5-4 82% +9 -114BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/157:00 PM Florida 3-6 82% +11½ -110Bet365
#7Ole Miss 9-1 18% -11½ -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/157:00 PM Purdue 2-8 92% +16½ -108Caesars
Washington 6-3 8% -16½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/157:00 PM Utah State 5-4 88% +6½ -112FanDuel
UNLV 7-2 12% -6 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/157:30 PM #10Texas 7-2 32% +6½ -110BetMGM
#5Georgia 8-1 68% -6 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/157:30 PM Virginia Tech 3-6 85% +14 -110Caesars
Florida State 4-5 15% -13½ -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/157:30 PM UCLA 3-6 65% +32 -112BetRivers
#1Ohio State 9-0 35% -31½ -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/157:45 PM Mississippi State 5-5 73% +7 -110Bet365
Missouri 6-3 27% -6½ -118FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/158:00 PM Kennesaw State 7-2 25% -2½ -130BetRivers
Jacksonville State 6-3 75% +3½ -118FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1510:00 PM Louisiana Tech 5-4 92% +8½ +100Caesars
Washington State 4-5 8% -7½ -115Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1510:15 PM TCU 6-3 89% +4½ -110Bet365
#12Brigham Young 8-1 11% -3 -122BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1510:30 PM Wyoming 4-5 71% +3½ -110Bet365
Fresno State 6-3 29% -3½ -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/1510:30 PM Boise State 6-3 63% +3 -115Bet365
San Diego State 7-2 37% -1½ -112FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FINAL OTTUE 11/117:30 PM Kent State 4-6 42 +7½ -112FanDuel
Akron 4-7 35 -7 -118SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTUE 11/118:00 PM Ohio 6-4 13 +1½ -110Caesars
Western Michigan 6-4 17 +2 -139SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. FINALWED 11/127:00 PM Northern Illinois 3-7 45 -9½ -109Caesars
Massachusetts 0-10 3 +10 -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. FINALWED 11/127:00 PM Toledo 6-4 24 -5½ -110SugarHouse
Miami (OH) 5-5 3 +5½ -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FINALWED 11/127:00 PM Buffalo 5-5 19 +2½ -105Bet365
Central Michigan 6-4 38 -2½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 11/137:30 PM Troy 6-4 0 +10 -110Bet365
Old Dominion 7-3 33 -9 -115BetRivers

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