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FINAL
Oct 25, 2025 3:30 PM EDT
BYU 41 vs ISU 27
Week 9
12-2
#10 Brigham Young
41
FINAL
27
8-4
Iowa State
ISU
-2½ (-118)o49 (-107)
tvFOX
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Betting Trends BYU Cougars vs Iowa State Cyclones

Updated:Oct 25, 2025 2:53 AM EDT

The upcoming Saturday football game on October 25, 2025, features an exciting NCAAF matchup between the BYU Cougars and the Iowa State Cyclones at Jack Trice Stadium in Ames, IA. This game offers key betting trends and game insights that bettors should consider before placing their wagers. The Cyclones, favored by -2.5 points with a total points line set at 48.5, hold a slight edge due to their solid home record and defensive stats.

BYU's offense averages 203.9 passing yards and 232.9 rushing yards per game, while Iowa State counters with a balanced defense allowing 203.7 passing yards and 163.1 rushing yards. The Cougars' starting quarterback has been effective, but Iowa State's defense excels in pass protection and pass rush, creating a potential challenge for BYU's passing game. Meanwhile, Iowa State's offense averages 242.1 passing yards and 163.1 rushing yards, presenting a balanced attack against BYU's defense that allows 171.4 passing yards and 121.6 rushing yards on average.

Injuries appear manageable, with key players likely to play, adding to the competitive nature of this game. Recent betting trends show BYU with a 5-2 ATS record and Iowa State at 3-3-1 ATS, illustrating a competitive betting landscape. The game will be broadcast on Fox, making it accessible for fans and bettors alike.

For bettors looking to capitalize, understanding these betting stats and trends is crucial. The point spread and total points line suggest a moderately close game with scoring potential, making the Cyclones a smart pick at home. The Cougars' aggressive offense might push the total points over the line, but Iowa State's defense could keep it in check. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

Check out their last matchup on November 11, 2023, where Iowa State defeated BYU 45-13 for more context on their head-to-head performance.

Where can I watch the BYU Cougars vs Iowa State Cyclones game?

ATS Records

Brigham Young

Iowa State

All
  • All
  • 1st half
  • 2nd half
  • 1st quarter
  • 2nd quarter
  • 3rd quarter
  • 4th quarter
10-4 (16th)Against the Spread5-6-1 (172nd)
12-2 (10th)Straight Up8-4 (75th)
+4.4Straight Up Units+1.9
6-8Over / Under4-8

TEAM MATCHUP

Brigham Young

Iowa State

OFF
DEF
OFF
DEF
31.4Points27.4
399.5Total Yards395.9
6.2Yards Per Play6
221.1Passing Yards221.4
18.4 - 28.8 (63.8%)Completions-Attempts17.5 - 28.9 (60.5%)
7.7Yards Per Passing Play7.7
6.9Sacks-Yards Lost12.1
178.4Rushing Yards174.5
37.9Attempts39.8
4.7Yards Per Rush4.4
21.91st Downs21.1
9.5Passing9.9
10.6Rushing9.5
1.7Penalties1.7
5.4 / 12.9 (41.4%)3rd Down5.4 / 13.5 (40.1%)
1.3 / 2.2 (58.1%)4th Down1.6 / 2.3 (67.9%)
3.8 / 4.2 (89.8%)Red Zone3.5 / 4.3 (80.8%)
5.4 (45.4)Penalties (Yards)4.6 (40)
0.5Interceptions0.8
0.6Fumbles Lost0.4
67.9Total Plays70.4
6.2Kickoffs5.4
1.4Returns0.9
33.2Yards15.8
23.3Yards Per Return17.3
2.9Punts3.6
1.9Returns1
21.6Yards17.8
11.7Yards Per Return17.8

Recent Results

Brigham Young

Iowa State

Game
Score
ATS
O/U
vs Utah
Oct 18, 2025
W
24-21
W
+4½
U
49
at Arizona
Oct 11, 2025
W
33-27
W
-2½
O
46½
vs West Virginia
Oct 3, 2025
W
38-24
L
-20
O
46½
at Colorado
Sep 27, 2025
W
24-21
L
-6½
U
48½
at East Carolina
Sep 20, 2025
W
34-13
W
-6½
U
50
vs Stanford
Sep 6, 2025
W
27-3
W
-20½
U
44½
vs Portland State
Aug 30, 2025
W
69-0
W
-43½
O
62½
at Colorado
Dec 28, 2024
W
36-14
W
+3
U
54½
vs Houston
Nov 30, 2024
W
30-18
L
-12½
O
40½
at Arizona State
Nov 23, 2024
L
23-28
L
+3½
O
49½
Game
Score
ATS
O/U
at Colorado
Oct 11, 2025
L
17-24
L
-3
U
52
at Cincinnati
Oct 4, 2025
L
30-38
L
+1½
O
55½
vs Arizona
Sep 27, 2025
W
39-14
W
-4
O
48½
at Arkansas State
Sep 13, 2025
W
24-16
L
-21½
U
55½
vs Iowa
Sep 6, 2025
W
16-13
P
-3
U
43
vs South Dakota
Aug 30, 2025
W
55-7
W
-16½
O
47½
at Kansas State
Aug 23, 2025
W
24-21
W
+3
U
51½
at Miami (FL)
Dec 28, 2024
W
42-41
W
+5
O
62
at Arizona State
Dec 7, 2024
L
19-45
L
-1½
O
50½
vs Kansas State
Nov 30, 2024
W
29-21
W
-1½
U
51½
View Full Season Game Log

HEAD TO HEAD

Brigham Young

BYU

Iowa State

ISU
Matchup
SU
ATS
O/U
Iowa State @ Brigham YoungNov 11, 2023
45-13
ISU
-7½
ISU
41
O

Brigham Young

UPCOMING SCHEDULE

Iowa State

Matchup
Date
Time
at Texas Tech
tvABC, ESPN Networks
Nov 8, 2025
12:00 EST
vs TCU
tvESPN, 206
Nov 15, 2025
22:15 EST
at Cincinnati
tvFOX
Nov 22, 2025
20:00 EST
vs UCF
tvESPN2, 209
Nov 29, 2025
13:00 EST
at Texas Tech
tvABC
Dec 6, 2025
12:00 EST
Matchup
Date
Time
vs Arizona State
tvTNT, 245
Nov 1, 2025
13:00 EDT
at TCU
tvFOX
Nov 8, 2025
15:30 EST
vs Kansas
tv219, FOX Sports 1
Nov 22, 2025
12:00 EST
at Oklahoma State
tv208, ESPNU
Nov 29, 2025
12:00 EST
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