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Get ready for an exciting match-up as the Carolina Panthers take on the Arizona Cardinals on September 14, 2025, at State Farm Stadium in Glendale, AZ. This NFL Week 2 showdown promises to deliver thrilling Sunday football action, broadcasted live on CBS. Our prediction model gives the Cardinals a 72.8% hit rate to win, with a predicted score of 27-20. The over/under is set at 43.5, and our data suggests going over, with a predicted total score of 47. This game is pivotal for both teams as they aim to establish their dominance early in the season. The Panthers, coming off a loss to the Jacksonville Jaguars, are eager to bounce back, while the Cardinals, fresh from a win against the New Orleans Saints, look to continue their momentum. Our betting tips have been profitable with a 58% hit rate on the American Total market in recent games. Explore more NFL picks and start your OddsTrader Turbo subscription today to gain an edge in your betting strategy.
![]() Pittsburgh 2-144% +3 -121SugarHouse | |||||||
![]() Tampa Bay 3-064% +3½ -110Caesars | |||||||
Buffalo 3-032% -15 -120BetMGM | |||||||
New England 1-241% -5½ -106Caesars | |||||||
![]() Atlanta 1-273% +1½ -114SugarHouse | |||||||
Detroit 2-114% -9½ -110FanDuel | |||||||
![]() Houston 0-325% -7 -109Caesars | |||||||
![]() N.Y. Giants 0-377% +6½ -110Caesars | |||||||
![]() San Francisco 3-035% -3 -117BetRivers | |||||||
![]() L.A. Rams 2-134% -3 -120SugarHouse | |||||||
![]() Las Vegas 1-258% -½ -112BetRivers | |||||||
![]() Kansas City 1-260% +3 -115BetRivers | |||||||
Dallas 1-261% +7 -115BetMGM | |||||||
Miami 0-331% -2½ -115Caesars | |||||||
Denver 1-28% -7½ -105Bet365 | |||||||
Arizona 2-220 +2 -109SugarHouse |
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