Sep 25, 2025 8:15 PM EDT

Week 4

Seattle

2-1

Arizona

SEA

-1½ (-110)o43½ (-110)

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Seattle Seahawks vs Arizona Cardinals Betting Trends

Updated:Sep 25, 2025 4:00 AM EDT

In an electrifying Thursday night football matchup on September 25, 2025, the Seattle Seahawks will face off against the Arizona Cardinals at State Farm Stadium in Glendale, AZ. This highly anticipated game promises intense action and strategic plays, with both teams eager to secure a win in the NFL's Week 4. The Seahawks, led by starting quarterback Sam Darnold, have shown a robust pass offense, averaging 219 passing yards per game, which will test the Cardinals' defensive capabilities. Meanwhile, the Cardinals' Kyler Murray is expected to lead the charge, aiming to exploit Seattle's defensive vulnerabilities.

Seattle's recent form includes a dominant 44-13 victory over the New Orleans Saints, highlighting their offensive prowess. However, their defense will need to tighten up against Arizona's varied attacks. The Cardinals, on the other hand, have been inconsistent but demonstrated their potential with a 20-13 win against the New Orleans Saints earlier this season.

The Seahawks are slight favorites with a -1.5 point spread, and the total points are set at 43.5. This game presents a fascinating clash of styles, with the Seahawks' pass protection needing to counter the Cardinals' pass rush effectively. Understanding these betting insights can guide your wagering decisions and potentially lead to profitable outcomes. Catch the action live on Amazon Prime Video.

What are the betting odds for the Seahawks vs Cardinals game?

ATS Records

Seattle

Arizona

All

All
1st half
2nd half
1st quarter
2nd quarter
3rd quarter
4th quarter

2-1 (3rd)Against the Spread2-1 (16th)

2-1 (15th)Straight Up2-1 (7th)

+0.8Straight Up Units-0.4

2-1Over / Under1-2

TEAM MATCHUP

Seattle

Arizona

OFF

DEF

OFF

DEF

29.3Points20.7

18.3First Half13.3

11Second Half7.3

9.3First Quarter4.3

9Second Quarter9

4.3Third Quarter4.3

6.7Fourth Quarter3

315Total Yards276.3

6Yards Per Play5.2

219Passing Yards165

18 - 25.7 (70.1%)Completions-Attempts20 - 29.7 (67.4%)

8.2Yards Per Passing Play5.2

1 (7)Sacks (Yards)2.3 (16)

96Rushing Yards111.3

29.3Attempts25.7

3.3Yards Per Rush4.3

191st Downs17

10Passing9.7

7Rushing5.7

2Penalties1.7

4 / 11 (36.4%)3rd Down4.7 / 12.3 (37.8%)

0.3 / 0.7 (50%)4th Down1 / 1 (100%)

2.3 / 3.7 (63.6%)Red Zone1.7 / 3.3 (50%)

4.7 (36.7)Penalties (Yards)8.7 (60)

2.7Turnovers0.7

1.7Interceptions0.7

1Fumbles Lost0

55Total Plays55.4

6.3Kickoffs5

3Returns3.7

94.7Return Yards91.7

31.6Yards Per Return25

3.7Punts3.7

2Returns1.7

52Return Yards22.3

26Yards Per Return13.4

Priority Injuries

Seattle

Arizona

No priority injuries for this team

PRIORITY

James Conner

Injury Reserve

Est. Return Feb 9, 2026

6 Running Back

a day ago

HEAD TO HEAD

Seattle

SEA

Arizona

ARI

NFL

ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

Spread

Spread
Money
Total
Merged

Game

Game
1H
2H
1Q
2Q
3Q
4Q

This Week

Last Week

Personalize your notifications and get updates on the teams, players or events you care about most. THU 09/258:15 PM Seattle 2-1 29% -1½ -108FanDuel
Arizona 2-1 71% +2 -109BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/289:30 AM Minnesota 2-1 56% -2 -120BetMGM
Pittsburgh 2-1 44% +2½ -106FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Philadelphia 3-0 33% -3½ -105FanDuel
Tampa Bay 3-0 67% +3½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM New Orleans 0-3 78% +15½ -109Caesars
Buffalo 3-0 22% -15 -120BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Carolina 1-2 71% +5½ -110Caesars
New England 1-2 29% -5½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Washington 2-1 30% -1 -105BetMGM
Atlanta 1-2 70% +1½ -112FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Cleveland 1-2 86% +10 -112Caesars
Detroit 2-1 14% -9½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM Tennessee 0-3 72% +7½ -122FanDuel
Houston 0-3 28% -7 -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/281:00 PM L.A. Chargers 3-0 22% -6½ -105FanDuel
N.Y. Giants 0-3 78% +6½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:05 PM Jacksonville 2-1 70% +3½ -115Caesars
San Francisco 3-0 30% -3 -117BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:05 PM Indianapolis 3-0 55% +3½ -112FanDuel
L.A. Rams 2-1 45% -3½ -105Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:25 PM Chicago 1-2 18% +1½ -118FanDuel
Las Vegas 1-2 82% -½ -114SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/284:25 PM Baltimore 1-2 33% -2½ -110Caesars
Kansas City 1-2 67% +3 -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 09/288:20 PM Green Bay 2-1 21% -6½ -110Caesars
Dallas 1-2 79% +7 -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. MON 09/297:15 PM N.Y. Jets 0-3 72% +3 -115BetRivers
Miami 0-3 28% -2½ -115Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. MON 09/298:15 PM Cincinnati 2-1 91% +7½ -110Caesars
Denver 1-2 9% -7 -120SugarHouse

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Seattle Seahawks vs Arizona Cardinals Betting Trends

ATS Records

Seattle

Arizona

TEAM MATCHUP

Seattle

Arizona

Priority Injuries

Seattle

Arizona

Recent Results

Seattle

Arizona

HEAD TO HEAD

Seattle

Arizona

Seattle

UPCOMING SCHEDULE

Arizona