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Before the highly anticipated clash on October 13, 2025, between the Buffalo Bills and Atlanta Falcons at Mercedes-Benz Stadium in Atlanta, GA, fans and bettors alike are buzzing with excitement. This Monday night football game promises to deliver intense action as the Buffalo Bills, led by their dynamic quarterback Josh Allen, take on the Atlanta Falcons. Allen has been in stellar form, with Buffalo's pass offense averaging 241.4 yards per game, one of the best in the NFL. Meanwhile, Atlanta's defense will need to step up, especially considering their recent struggles against high-caliber offenses.
The Falcons, playing at home, will rely heavily on their run game, spearheaded by Bijan Robinson, to counter Buffalo's formidable pass rush led by Joey Bosa. Atlanta's Kirk Cousins, stepping in as quarterback, will face a tough challenge against a Buffalo defense that has limited opponents to 154 passing yards per game. The betting trends indicate a slight edge for Buffalo, favored by 3.5 points, with a total points line set at 48.5.
For bettors, the key will be Atlanta's ability to protect Cousins and establish their ground game early. With ESPN covering the game, fans will have ample opportunity to witness if Atlanta can exploit Buffalo's defensive vulnerabilities. Given the spread and total points, betting insights suggest a close game with potential for a high-scoring affair, especially if Atlanta can capitalize on home-field advantage.
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![]() N.Y. Giants 1-477% +7½ -110FanDuel | |||||||
![]() N.Y. Jets 0-584% +7½ -115Caesars | |||||||
![]() Pittsburgh 3-137% -5 -109BetRivers | |||||||
![]() Indianapolis 4-18% -6½ -105FanDuel | |||||||
![]() Baltimore 1-479% +7½ -109Caesars | |||||||
Jacksonville 4-10% +1½ -118Caesars | |||||||
Carolina 2-394% +3½ -112BetRivers | |||||||
Miami 1-488% +4½ -104FanDuel | |||||||
New Orleans 1-488% +3½ -105FanDuel | |||||||
![]() Las Vegas 1-431% -4½ -110Bet365 | |||||||
![]() Tampa Bay 4-124% -3 -105FanDuel | |||||||
Green Bay 2-1-112% -14½ -105BetMGM | |||||||
![]() Kansas City 2-3100% +1 -110BetMGM | |||||||
![]() Atlanta 2-291% +4 -112BetRivers | |||||||
![]() Washington 3-217% -4½ -105FanDuel |
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