Betting Trends: Falcons vs Panthers

Before the Atlanta Falcons take on the Carolina Panthers on September 21, 2025, at Bank of America Stadium in Charlotte, NC, NFL fans are buzzing with anticipation. This Sunday football matchup, broadcasted on FOX, promises to be a thrilling contest. The Atlanta Falcons, led by quarterback Michael Penix Jr., are favored with a -5 point spread according to Caesars. Meanwhile, the Carolina Panthers, under the leadership of quarterback Bryce Young, look to capitalize on their home advantage. The Panthers have faced some challenges recently, especially with injuries like that of cornerback Patrick Jones II, who is out for this game. For bettors, the game insights suggest focusing on the Falcons' potent pass offense against the Panthers' vulnerable pass defense. In their last encounter, the Panthers edged out the Falcons 44-38, a high-scoring affair that went over the projected total of 48.5 points. With the current over/under set at 44 points, bettors might consider leaning towards the over, given both teams' recent scoring trends. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. Don’t forget to check out our previous matchup from January 5, 2025 where the Panthers triumphed 44-38.