Player Props: New England Patriots vs Buffalo Bills

The upcoming Sunday Night Football clash on October 5, 2025, between the New England Patriots and Buffalo Bills at Highmark Stadium in Orchard Park, NY promises a thrilling encounter in the NFL. The Patriots are set to face the Bills with a focus on exploiting their defensive weaknesses, particularly in the passing game. Drake Maye's player props are especially enticing, with an over 33.5 on longest passing completion showing an impressive 80.9% hit rate. Meanwhile, Rhamondre Stevenson's rushing and receiving yards are another high-value prop bet, boasting a 75.7% hit rate.

Buffalo's James Cook III also presents a compelling case with his rushing and receiving yards prop bet, holding a 75.4% hit rate, making it a strategic play for bettors. The Bills' defense will need to step up, particularly against the Patriots' passing offense, to secure a win. The game will be broadcasted on NBC, offering ample opportunity for fans to tune in and place bets.

For those keen on diving deeper into player projections, our last 10 games have shown solid profits, particularly in passing yards markets. With the Patriots' pass offense pitted against the Bills' pass defense, this matchup is ripe for strategic betting. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. Explore more on our NFL player props page.