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Dec 14, 2025 1:00 PM EST
Week 15
BUF
-1 (-110)o49½ (-113)
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Buffalo Bills vs New England Patriots Picks
Updated:Dec 11, 2025 1:21 AM EST
The upcoming NFL clash on December 14, 2025, between the Buffalo Bills and New England Patriots at Gillette Stadium in Foxborough, MA, is set to be an exciting Sunday football matchup. This game will be broadcast on CBS, making it accessible for fans and bettors alike. Our expert picks and predictions give the Buffalo Bills a slight edge with a predicted score of 27 to 23, and we favor Buffalo -1 on the point spread. The predicted total score is around 49.6, suggesting a game that could go over or under the set line of 49.5 points.
Our prediction model has been profitable in recent NFL games, winning 6 out of the last 10 in the point spread market, which has a strong hit rate of 57.4% and a positive EV of 5.5%. This insight supports our confidence in the Buffalo Bills covering the spread this Sunday. Bettors can leverage these picks and betting tips to make smarter wagers for this exciting NFL Week 15 matchup. For more detailed NFL picks and predictions, check out our comprehensive NFL picks page.
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UPCOMING GAME PREDICTION
Spread
Money
Total
BUFSpread
CONSENSUS LINE
-1 (-110)
PROJECTION
NE (23) - BUF (27)
COVER PROBABILITY
EXPECTED VALUE
+5.5%
BET RATING
SEASON COVER %
6/13
46%
OTHER BETS
Sun 12/14 1:00 PMBUF @ NE
Drake MayePlayer Longest Passing Completion
EV
+26.2%
+26.2%
Drake MayePassing + Rushing Yards
EV
+21.2%
+21.2%
James Cook IIIRushing + Receiving Yards
EV
+18.5%
+18.5%
TreVeyon HendersonRushing + Receiving Yards
EV
+12.2%
+12.2%
Drake MayePassing Yards
EV
+12.0%
+12.0%
Josh AllenPassing + Rushing Yards
EV
+11.6%
+11.6%
Demario DouglasPlayer to score first touchdown
EV
+8.6%
+8.6%
Josh AllenPlayer to score first touchdown
EV
+8.3%
+8.3%
James Cook IIIAnytime Touchdown Scorer
EV
+8.2%
+8.2%
Kayshon BoutteAnytime Touchdown Scorer
EV
+8.1%
+8.1%
NFL
Spread
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This Week
Last Week
NFLWeek 15
 Tampa Bay 7-641% -4½ -110Caesars | |||||||
 Houston 8-518% -9 -114SugarHouse | |||||||
 Philadelphia 8-515% -10½ -115SugarHouse | |||||||
 Jacksonville 9-429% -12½ -115SugarHouse | |||||||
 Chicago 9-413% -7½ -109BetRivers | |||||||
 New England 11-255% +1½ -115FanDuel | |||||||
 Cincinnati 4-930% +2½ -105BetMGM | |||||||
 Kansas City 6-755% -5½ -105FanDuel | |||||||
 N.Y. Giants 2-1145% -2½ -110BetMGM | |||||||
 Seattle 10-314% -13½ -113Caesars | |||||||
 Denver 11-228% +2½ -110BetMGM | |||||||
 New Orleans 3-1062% +3 -121SugarHouse | |||||||
 L.A. Rams 10-355% -5½ -114BetRivers | |||||||
 San Francisco 9-44% -12½ -110Bet365 | |||||||
 Dallas 6-6-123% -5½ -110Bet365 | |||||||
 Pittsburgh 7-629% -3½ -105BetMGM |
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