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Get ready for an exciting NFL showdown on January 4, 2026, as the N.Y. Jets take on the Buffalo Bills at Highmark Stadium in Orchard Park, NY. This Week 18 Sunday football game promises intense action and plenty of betting opportunities. The game will be broadcast on CBS, making it easy to catch all the live drama.
Our expert picks predict a Buffalo Bills victory with a final score of 21-17, covering the spread with Buffalo favored by 7.5 points. The predicted total score is just under 39.5, aligning with a betting strategy favoring the under. With our prediction model showing a strong hit rate in recent games, particularly in point spread markets, bettors have an edge here. Our model has been profitable in the last 10 games, winning 6 of them, especially in American Total and point spread markets, which show high expected value and solid cover percentages.
Use these insights to make informed bets and explore our NFL picks page for more detailed analysis and predictions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Tampa Bay 7-942% -2½ -113Caesars | |||||||
![]() San Francisco 12-432% +1½ -114SugarHouse | |||||||
Minnesota 8-875% -5½ -120FanDuel | |||||||
![]() Houston 11-533% -10 -110Bet365 | |||||||
![]() Cincinnati 6-1017% -7½ -107BetRivers | |||||||
![]() N.Y. Giants 3-1375% +5½ -105FanDuel | |||||||
![]() Atlanta 7-967% -2½ -117BetRivers | |||||||
Jacksonville 12-40% -11½ -110BetRivers | |||||||
New England 13-30% -10½ -118FanDuel | |||||||
![]() Las Vegas 2-1440% +5½ -105FanDuel | |||||||
![]() Chicago 11-550% -2 -120BetMGM | |||||||
Buffalo 11-59% -7 -110Bet365 | |||||||
Philadelphia 11-50% -7½ -110Bet365 | |||||||
![]() L.A. Rams 11-5- -7 -112FanDuel | |||||||
Denver 13-333% -11½ -110FanDuel | |||||||
![]() Pittsburgh 9-777% +3½ -113Caesars |
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