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The upcoming NFL clash on November 30, 2025, between the Buffalo Bills and the Pittsburgh Steelers at Acrisure Stadium in Pittsburgh, PA, promises an exciting Sunday football showdown. The Bills, led by starting quarterback Josh Allen, bring a potent offense averaging 28.27 points per game, with a strong passing attack that tallies 234.64 passing yards per game. However, they face a tough Steelers defense that allows just 23.91 points on average and boasts a formidable pass rush with 3.09 sacks per game. The Steelers will counter with their starting QB, Aaron Rodgers, who has been effective managing the game, supported by a balanced offense averaging 24.91 points per game and a solid run game producing 97.09 rushing yards per game. Pittsburgh's defense is known for its resilience, ranking well against both the pass and the run, and their pass rush could challenge Allen's protection, which has allowed 16.55 sacks this season.
Injuries play a key role, with the Bills missing key defensive players like Michael Hoecht and Landon Jackson, while the Steelers are without several defensive starters including DeShon Elliott and Isaiahh Loudermilk. Buffalo's offensive line has some question marks with Spencer Brown out, potentially impacting pass protection. The odds favor the Bills by 3 points with an over/under of 45.5, indicating a moderately high-scoring game. Bettors should consider the Bills' strong offensive stats and the Steelers' stout defense when making wagers. Past matchups show Buffalo has dominated recently, including a decisive 31-17 win on January 15, 2024, which can be reviewed in their last matchup details.
This game airs on CBS, making it accessible for fans eager to catch every moment of this pivotal Week 13 game. With betting trends favoring Buffalo slightly but Steelers showing home strength, this matchup offers intriguing betting insights. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Indianapolis 8-348% -3 -110Caesars | |||||||
![]() Tampa Bay 6-526% -3½ -110BetMGM | |||||||
![]() Tennessee 1-1064% +6½ -120FanDuel | |||||||
Carolina 6-667% +10½ -110Caesars | |||||||
Miami 4-724% -5 -115Bet365 | |||||||
![]() N.Y. Jets 2-973% +3 -105Bet365 | |||||||
Cleveland 3-842% +5½ -105Caesars | |||||||
Seattle 8-343% -10½ -105FanDuel | |||||||
![]() Pittsburgh 6-571% +3 -105Bet365 | |||||||
![]() L.A. Chargers 7-418% -9 -114SugarHouse | |||||||
![]() Washington 3-853% +6½ -105Bet365 | |||||||
New England 10-223% -7 -109Caesars | |||||||
Detroit 7-524 -3 -105BetMGM | |||||||
Dallas 6-5-131 +3½ -110BetMGM | |||||||
![]() Baltimore 6-614 -7½ -114BetRivers | |||||||
Philadelphia 8-415 -7 -110BetMGM |
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