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As the Cleveland Browns prepare to take on the Detroit Lions on September 28, 2025, NFL fans and bettors are gearing up for an exciting matchup. The game will be held at Ford Field in Detroit, MI, and will be broadcast on FOX. This Sunday football clash promises to be a thrilling encounter, with the Lions coming in as the favorites with a point spread of -3.5 at Caesars.
The Browns, led by quarterback Joe Flacco, will rely on their strong pass offense to challenge the Lions' defense, which has been vulnerable, allowing 245.333 passing yards per game. On the other hand, Jared Goff and the Lions boast a formidable pass offense, averaging 245.333 passing yards per game, which will test the Browns' defense. The Lions have been impressive with a 2-1-0 record and their strong home performance, making them a tough opponent for Cleveland.
In their last matchup on November 21, 2021, the Browns edged out the Lions with a close 13-10 victory. This time around, the Lions will be looking to capitalize on their home advantage and recent form. The over/under is set at 44.5, and with both teams showing offensive capabilities, betting on the over might be a smart move.
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![]() Pittsburgh 2-144% +3 -120SugarHouse | |||||||
![]() Tampa Bay 3-065% +3½ -110Caesars | |||||||
Buffalo 3-032% -15 -120BetMGM | |||||||
New England 1-240% -5½ -106Caesars | |||||||
![]() Atlanta 1-273% +1½ -114SugarHouse | |||||||
Detroit 2-114% -9½ -110FanDuel | |||||||
![]() Houston 0-325% -7 -109Caesars | |||||||
![]() N.Y. Giants 0-377% +6½ -110Caesars | |||||||
![]() San Francisco 3-035% -3 -117BetRivers | |||||||
![]() L.A. Rams 2-134% -3 -120SugarHouse | |||||||
![]() Las Vegas 1-257% -½ -112BetRivers | |||||||
![]() Kansas City 1-260% +3 -115BetRivers | |||||||
Dallas 1-261% +7 -115BetMGM | |||||||
Miami 0-330% -2½ -115Caesars | |||||||
Denver 1-28% -7½ -105Bet365 | |||||||
Arizona 2-220 +2 -109SugarHouse |
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