Dec 14, 2025 4:25 PM EST

Week 15

Detroit

10-3

L.A. Rams

-5½ (-110)o55½ (-105)

FOX

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Detroit Lions vs L.A. Rams Picks

Updated:Dec 10, 2025 1:20 AM EST

The upcoming NFL clash on December 14, 2025, features the Detroit Lions taking on the Los Angeles Rams at SoFi Stadium in Inglewood, California. This Sunday football game promises to be a thrilling matchup in the 2025-26 NFL season. Fans can catch the action live on Fox as the Lions look to challenge the Rams on their home turf.

Our picks for this game are backed by solid betting insights. We predict a close contest with the Rams edging out the Lions 29-27. The spread favors the Lions at +5.5, which aligns with a 56.5% hit rate and a 5.3% EV, making it a smart bet choice. Additionally, the predicted total score is 55.67, suggesting a high-scoring game that slightly leans over the 54.5 line, which has a near 50% coverage percentage and is an interesting option for over bettors.

Our prediction model has been profitable recently, winning 6 out of the last 10 games on point spreads, especially favoring markets with a high EV and strong hit rate. These stats can help bettors make informed decisions and maximize their betting potential. For more detailed NFL insights and expert picks, check out our comprehensive NFL picks page.

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ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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Personalize your notifications and get updates on the teams, players or events you care about most. THU 12/118:15 PM Atlanta 4-9 63% +5 -118BetMGM
Tampa Bay 7-6 37% -4 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/141:00 PM Arizona 3-10 83% +9½ -105BetMGM
Houston 8-5 17% -9½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/141:00 PM Las Vegas 2-11 81% +11½ -115FanDuel
Philadelphia 8-5 19% -10½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/141:00 PM N.Y. Jets 3-10 74% +12½ -110Bet365
Jacksonville 9-4 26% -11½ -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/141:00 PM Cleveland 3-10 93% +7½ -110Caesars
Chicago 9-4 7% -7½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/141:00 PM Buffalo 9-4 47% -1 -105Bet365
New England 11-2 53% +1½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/141:00 PM Baltimore 6-7 67% -2½ -110Bet365
Cincinnati 4-9 33% +2½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/141:00 PM L.A. Chargers 9-4 35% +4½ -108FanDuel
Kansas City 6-7 65% -4½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/141:00 PM Washington 3-10 55% +2½ -112FanDuel
N.Y. Giants 2-11 45% -2 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/144:25 PM Indianapolis 8-5 89% +13½ -110Caesars
Seattle 10-3 11% -13½ -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/144:25 PM Green Bay 9-3-1 82% -2 -114BetRivers
Denver 11-2 18% +2½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/144:25 PM Carolina 7-6 45% -2½ -115Caesars
New Orleans 3-10 55% +3 -121SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/144:25 PM Detroit 8-5 50% +5½ -105FanDuel
L.A. Rams 10-3 50% -5½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/144:25 PM Tennessee 2-11 93% +12½ -106Caesars
San Francisco 9-4 7% -12½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/148:20 PM Minnesota 5-8 70% +6½ -115FanDuel
Dallas 6-6-1 30% -5½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. MON 12/158:15 PM Miami 6-7 65% +3½ -112Caesars
Pittsburgh 7-6 35% -3½ -105Bet365

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