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Get ready for an electrifying matchup as the Houston Texans take on the Jacksonville Jaguars on September 21, 2025, at EverBank Stadium in Jacksonville, FL. This NFL showdown is set to thrill football fans and bettors alike, with both teams eager to assert dominance in the league. The Texans, led by quarterback C.J. Stroud, will aim to exploit Jacksonville's defense, which has shown vulnerabilities in passing yards allowed. Houston's pass offense, averaging 166.5 yards, will face a stiff test against Jacksonville's defensive line.
Meanwhile, the Jaguars, with Trevor Lawrence at the helm, boast a potent offensive strategy, aiming to capitalize on Houston's defensive inconsistencies. Jacksonville's run game, spearheaded by Travis Etienne Jr., averages 169.5 rushing yards and could be pivotal against Houston's defense, which struggles to contain ground attacks.
The betting trends lean slightly towards the Jaguars, favored by -1.5 points at Caesars. With a total points line set at 43.5, expect a tight contest. Houston's recent form shows a string of close games, while Jacksonville aims to bounce back from a narrow loss to the Bengals.
Catch the action live on CBS and make informed bets by checking out the Start your OddsTrader Turbo subscription for the latest insights. With both teams having a history of competitive games, as seen in their last matchup, which ended 23-20 in favor of Houston, this game promises to be another thrilling chapter. Ready to bet smarter? Caesars offers the best odds for this clash.
![]() Tennessee 0-272% +4½ -118FanDuel | |||||||
Carolina 0-279% +5½ -110Bet365 | |||||||
![]() Washington 1-136% -3 -105Caesars | |||||||
Cleveland 0-278% +8 -110BetMGM | |||||||
Minnesota 1-150% -3 -105BetMGM | |||||||
Philadelphia 2-044% -3 -125Caesars | |||||||
New England 1-160% +2 -110Caesars | |||||||
![]() Tampa Bay 2-019% -6½ -110Caesars | |||||||
Jacksonville 1-161% -1½ -110Caesars | |||||||
![]() L.A. Chargers 2-031% -2½ -118BetRivers | |||||||
Seattle 1-120% -7½ -105Bet365 | |||||||
![]() Chicago 0-281% +1½ -110FanDuel | |||||||
![]() San Francisco 2-051% -2 -109BetRivers | |||||||
![]() N.Y. Giants 0-277% +6½ -110BetMGM | |||||||
![]() Baltimore 1-129% -4½ -110Caesars | |||||||
Buffalo 3-031 -11 -110Bet365 |
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