Dec 7, 2025 1:00 PM EST

Week 14

Indianapolis

8-4

Jacksonville

IND

-1½ (-110)o47½ (-110)

CBS

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Indianapolis Colts vs Jacksonville Jaguars Picks

Updated:Dec 2, 2025 1:30 AM EST

The upcoming NFL clash on December 7, 2025, between the Indianapolis Colts and Jacksonville Jaguars at EverBank Stadium in Jacksonville, FL, promises an exciting Sunday football showdown. This regular season Week 14 game will be broadcast on CBS, giving fans a prime viewing opportunity.

Our picks favor the Indianapolis Colts with a predicted score of 27 to 22 over the Jaguars. The Colts are expected to cover the spread at -2, supported by a strong 55.3% hit rate and an EV of 3.4% on the point spread market. Meanwhile, the over 47.5 total points market shows a predicted total score of approximately 48.8, with a solid 50.8% cover percentage, indicating a potentially high-scoring game.

Recent performance insights reveal that our prediction model has been particularly profitable in the last 10 games, especially on the 2-way market where the Colts have a 64.1% hit rate and an 8.1% EV, highlighting a favorable betting edge. This data-driven approach helps bettors make smart decisions by leveraging statistical trends and market efficiency.

For those looking to deepen their betting strategy, our detailed NFL picks and predictions can be found on the NFL picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

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ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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Personalize your notifications and get updates on the teams, players or events you care about most. THU 12/048:15 PM Dallas 6-5-1 62% +3 -105Caesars
Detroit 7-5 38% -3 -114FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Washington 3-9 63% +1½ -105FanDuel
Minnesota 4-8 37% -1½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Miami 5-7 22% -2½ -115BetMGM
N.Y. Jets 3-9 78% +3 -120Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Tennessee 1-11 92% +4 -109BetRivers
Cleveland 3-9 8% -3½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Pittsburgh 6-6 67% +6 -110Bet365
Baltimore 6-6 33% -5½ -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Seattle 9-3 22% -7 -110Caesars
Atlanta 4-8 78% +7½ -118BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Indianapolis 8-4 33% -1½ -110Bet365
Jacksonville 8-4 67% +2 -114SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM New Orleans 2-10 95% +9 -115Bet365
Tampa Bay 7-5 5% -8½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/071:00 PM Cincinnati 4-8 59% +6 -110BetMGM
Buffalo 8-4 41% -5½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/074:05 PM Denver 10-2 17% -7½ -110Caesars
Las Vegas 2-10 83% +8 -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/074:25 PM Chicago 9-3 46% +6½ -109Caesars
Green Bay 8-3-1 54% -6½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/074:25 PM L.A. Rams 9-3 17% -8 -110Caesars
Arizona 3-9 83% +8½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 12/078:20 PM Houston 7-5 78% +3½ -114Caesars
Kansas City 6-6 22% -3 -120Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. MON 12/088:15 PM Philadelphia 8-4 15% -2½ -120Bet365
L.A. Chargers 8-4 85% +3 -114Caesars

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