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The Indianapolis Colts are set to face the New England Patriots in a highly anticipated NFL matchup this week. The Colts are favored to win with a point spread of -2½ -115, while the Patriots are at +2½ -105. The opening odds were more balanced, indicating shifting expectations as game day approaches. Historically, both teams have displayed varying performances in similar matchups. Discover the latest NFL Odds for this exciting face-off.
![]() Tennessee 0-273% +4½ -106Caesars | |||||||
Carolina 0-277% +5½ -110Bet365 | |||||||
![]() Washington 1-138% -3 -105Caesars | |||||||
Cleveland 0-279% +8½ -115BetMGM | |||||||
Minnesota 1-150% -3 -105BetMGM | |||||||
Philadelphia 2-045% -3 -125Caesars | |||||||
New England 1-163% +2 -110Caesars | |||||||
![]() Tampa Bay 2-019% -6½ -110Caesars | |||||||
Jacksonville 1-161% -1½ -105BetMGM | |||||||
![]() L.A. Chargers 2-030% -2½ -118BetRivers | |||||||
Seattle 1-120% -7½ -105Caesars | |||||||
![]() Chicago 0-282% +1½ -110FanDuel | |||||||
![]() San Francisco 2-049% -2 -109BetRivers | |||||||
![]() N.Y. Giants 0-278% +6 -105Caesars | |||||||
![]() Baltimore 1-129% -4½ -110Caesars | |||||||
Buffalo 3-031 -11 -110Bet365 |
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