Dec 1, 2025 8:15 PM EST

Week 13

N.Y. Giants

10-2

New England

-7½ (-105)o46½ (-108)

ESPN, 206

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N.Y. Giants vs New England Patriots Picks

Updated:Nov 27, 2025 1:43 AM EST

The Monday night football clash on December 1, 2025, between the N.Y. Giants and New England Patriots at Gillette Stadium in Foxborough, MA, promises an intense NFL showdown. The New England Patriots, favored by 7 points, are predicted to win with a score of 26-20 over the Giants. Our picks leverage a strong prediction model that has maintained a profitable track record, with a hit rate of 48.8% on point spreads and a compelling 70.8% on moneyline bets over the last 10 games. This consistency in predictions provides bettors with valuable betting tips to make informed wagers.

Broadcasted on ESPN, this game is a must-watch for NFL fans and bettors alike. The predicted total score is approximately 47 points, suggesting a moderately high-scoring game. Bettors should consider the Patriots' strong home performance and the Giants' resilience on the road. Our betting insights emphasize the Patriots covering the spread, providing a high EV opportunity for smart bettors.

For more detailed NFL picks and to enhance your betting strategy, check out our comprehensive NFL picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

When is the N.Y. Giants vs New England Patriots game?

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Personalize your notifications and get updates on the teams, players or events you care about most. THU 11/271:00 PM Green Bay 7-3-1 69% +3 -110Bet365
Detroit 7-4 31% -2½ -120BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. THU 11/274:30 PM Kansas City 6-5 30% -3 -115Bet365
Dallas 5-5-1 70% +3½ -112Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. THU 11/278:20 PM Cincinnati 3-8 78% +7½ -115BetMGM
Baltimore 6-5 22% -7 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 11/283:00 PM Chicago 8-3 68% +7 -110BetMGM
Philadelphia 8-3 32% -7 -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM Houston 6-5 54% +4½ -114BetRivers
Indianapolis 8-3 46% -3½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM Arizona 3-8 63% +3 -118BetRivers
Tampa Bay 6-5 37% -2½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM Jacksonville 7-4 26% -6½ -110Caesars
Tennessee 1-10 74% +6½ -106FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM L.A. Rams 9-2 49% -10½ -105BetMGM
Carolina 6-6 51% +10½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM New Orleans 2-9 63% +5½ -105Bet365
Miami 4-7 37% -5½ -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM Atlanta 4-7 27% -2½ -115Bet365
N.Y. Jets 2-9 73% +3 -125BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/301:00 PM San Francisco 8-4 78% -4½ -110BetRivers
Cleveland 3-8 22% +5½ -118BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/304:05 PM Minnesota 4-7 33% +11½ -105Caesars
Seattle 8-3 67% -10½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/304:25 PM Buffalo 7-4 17% -3 -120Bet365
Pittsburgh 6-5 83% +3½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/304:25 PM Las Vegas 2-9 90% +10 -120BetMGM
L.A. Chargers 7-4 10% -9 -114SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/308:20 PM Denver 9-2 69% -5½ -110Bet365
Washington 3-8 31% +6 -114BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. MON 12/018:15 PM N.Y. Giants 2-10 85% +7½ -115Caesars
New England 10-2 15% -7 -118BetRivers

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