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FINAL OT
Nov 23, 2025 4:05 PM EST
JAX 27 vs ARI 24
Week 12
JAX
-2½ (-102)o47 (-106)
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Jacksonville Jaguars vs Arizona Cardinals Picks
Updated:Nov 23, 2025 1:18 AM EST
The upcoming NFL clash on November 23, 2025, between the Jacksonville Jaguars and Arizona Cardinals at State Farm Stadium in Glendale, AZ, promises an exciting Sunday football showdown. This Week 12 matchup will be broadcast on CBS, making it easy for fans and bettors to catch all the action live. Our picks favor the Jacksonville Jaguars to win with a predicted score of 26 to 20, covering the spread at -2.5. The total points are expected to stay under 47.5, aligning with our profitable under bet market that has shown a strong hit rate in recent games.
Our predictions model has been profitable in the last 10 games, winning 6 of them in point spread markets, which offers bettors a solid edge. With Jacksonville showing a 58.3% hit rate and positive expected value on the spread, this game is a strong candidate for smart betting decisions. Arizona has also shown value in close games but will face a tough challenge playing at home under the retractable dome of State Farm Stadium.
For those looking to place bets or explore parlays, our detailed picks and betting tips for the NFL season can be found on the NFL picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
UPCOMING GAME PREDICTION
Spread
Money
Total
JAXSpread
CONSENSUS LINE
-2½ (-105)
PROJECTION
ARI (20) - JAX (26)
COVER PROBABILITY
EXPECTED VALUE
+5.5%
BET RATING
SEASON COVER %
5/10
50%
NFL
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NFLWeek 1
 Seattle - -3½ -110BetOnline | |||||||
.png?d=100x100) L.A. Rams - -3 -120Bovada | |||||||
 Jacksonville - -7½ -101Bet105 | |||||||
 Cincinnati - -3½ -102Bet105 | |||||||
 Indianapolis - +3½ -110BetOnline | |||||||
 Pittsburgh - -2½ -122Bet105 | |||||||
 Houston - +1½ -120Bovada | |||||||
 Carolina - +2½ -102Bet105 | |||||||
 Tennessee - -2½ -110Bookmaker | |||||||
 Detroit - -7 -105Bet105 | |||||||
 L.A. Chargers - -10 -115Bookmaker | |||||||
 Las Vegas - -3 -120BetOnline | |||||||
 Philadelphia - -4 -103Bet105 | |||||||
 Minnesota - +1½ -115Bovada | |||||||
 N.Y. Giants - +3 -110MyBookie | |||||||
 Kansas City - -2½ -110MyBookie |
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