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The Houston Texans are set to face off against the Buffalo Bills on October 6, 2024, at NRG Stadium in Houston, TX. The game will be aired live on CBS at 1:00 PM. In their last matchup on October 3, 2021, the Buffalo Bills dominated with a 40-0 victory over the Texans, which you can explore further in the last matchup. This season, the Texans boast a strong home record (3-0), but their performance against the spread has been less impressive, ranking 29th overall. On the other hand, the Bills have struggled on the road with a 1-2 record. Key players like Josh Allen for the Bills and C.J. Stroud for the Texans will be pivotal in this clash. The starting quarterback for Buffalo, Josh Allen, is expected to lead the charge despite recent team injuries. The Texans will rely on C.J. Stroud, who has been consistent this season. Betting odds have Houston at -1.5, and with the total points set at 48, bettors have a lot to consider. Make sure to check our NFL standings page for the latest ATS records and insights.