Buffalo Bills vs Miami Dolphins Betting Trends

The upcoming Sunday football showdown on November 9, 2025, between the Buffalo Bills and the Miami Dolphins at Hard Rock Stadium in Miami Gardens, FL, is set to be a thrilling NFL regular season Week 10 matchup. The game will be broadcast live on CBS and features a compelling battle of betting trends and game insights that bettors won’t want to miss.

The Buffalo Bills come into this game as favorites with a -9 point spread and odds of -560 at Caesars, reflecting their strong form and solid offensive and defensive stats. Quarterback Josh Allen leads the Bills' attack, while the Dolphins will counter with Tua Tagovailoa, who is likely starting despite some key injuries on the Miami side. Both teams have shown strong passing games, but the Bills boast a superior pass offense averaging 224 yards compared to Miami's 194. The Dolphins have a slightly better pass defense, but Buffalo’s pass protection faces a challenge against Miami’s aggressive pass rush.

Buffalo's run offense, averaging 161.5 yards per game, outmatches Miami’s 97.2 yards, but Miami's run defense is fairly stout, making this a key matchup to watch. The Bills' defense has been effective in creating turnovers and limiting Miami’s scoring, which has averaged just 20 points per game recently. The total points line is set at 50, suggesting an over/under wager could be enticing given the offensive firepower on both sides.

Injuries could play a role, with Buffalo missing key defenders like Michael Hoecht and A.J. Epenesa, while Miami is without star wide receiver Tyreek Hill due to a knee injury. These absences might affect the pace and style of play. The Bills have a solid 4-4-0 ATS record overall and have shown resilience as an away team, while the Dolphins have struggled with a 4-5-0 ATS record.

Previous encounters have been close and competitive, including a recent September 18, 2025, game where Buffalo won 31-21, a matchup you can review in detail on our page. For bettors, understanding these betting trends and stats will help make smarter wagers. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.