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The upcoming matchup between the New England Patriots and the Buffalo Bills promises to be a thrilling contest. Scheduled for January 5, 2025, at 1:00 PM ET, this game will be held at the Gillette Stadium in Foxborough, MA, and broadcasted live on CBS. In their last matchup on December 22, 2024, the Patriots narrowly lost to the Bills with a final score of 21-24. The Patriots have struggled this season, with a record of 3-13-0, ranking 30th in the league. Meanwhile, the Bills boast an impressive 13-3-0 record, ranking 4th. You can view their complete standings on our NFL standings page. The Bills are favored to win with a point spread of -3.5, and the total points over/under is set at 36.5. Josh Allen, the Bills' starting quarterback, is expected to lead the team, while the Patriots may rely on Jacoby Brissett, given Drake Maye's questionable status. With Buffalo's strong offensive and defensive stats, the odds are in their favor, but the Patriots' home advantage and potential surprises keep the game intriguing for bettors.