Chiefs vs Bills: Game Preview, Stats & Betting Insights

The Kansas City Chiefs are set to face the Buffalo Bills at Highmark Stadium in Orchard Park, NY, on November 17, 2024, at 4:25 PM ET. This highly anticipated NFL matchup will be broadcast on CBS, promising a thrilling encounter between two top-tier teams. The Buffalo Bills, led by quarterback Josh Allen, have shown impressive form, boasting an 8-2-0 record, with a 4-0 streak at home. Their offensive prowess has been highlighted by an average of 222.5 passing yards per game, while their defense limits opponents to just 212.9 passing yards.

Meanwhile, the Kansas City Chiefs, with Patrick Mahomes at the helm, maintain a perfect 9-0-0 record, including 4-0 on the road. Their offensive efficiency is evident with 231.6 passing yards per game, complemented by a solid defense that allows only 206.7 passing yards. In their last matchup on January 21, 2024, the Chiefs narrowly defeated the Bills 27-24. The Chiefs' consistency can be explored further on our NFL standings page.

With a point spread of -2 for the Bills and an over/under of 46, bettors should consider the Chiefs' strong away record and the Bills' home advantage. The Bills are favorites with odds of -130, while the Chiefs are at +110, offering potential value for those backing the underdogs. Injuries could play a crucial role, with Buffalo's defensive end Dawuane Smoot on injured reserve, and Kansas City's wide receiver JuJu Smith-Schuster listed as questionable. This clash promises to be a strategic battle, potentially decided by key performances from star players on both sides.