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FINAL
Oct 5, 2025 8:20 PM EDT
NE 23 vs BUF 20
Week 5
BUF
-7½ (-105)o48½ (-115)
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New England Patriots vs Buffalo Bills Odds
Updated:Oct 5, 2025 3:02 AM EDT
Get ready for an electrifying clash on October 5, 2025, as the Buffalo Bills take on the New England Patriots at Highmark Stadium in Orchard Park, NY. This NFL Week 5 matchup promises to be a thrilling contest with the Bills looking to maintain their home advantage. The game will be broadcasted on NBC, providing fans nationwide a chance to catch the action live.
The current odds have the Buffalo Bills as the favorites with a point spread of -8 -105 at Caesars, while the New England Patriots are at +8 -115, indicating a highly competitive game. The over/under is set at 49 points, with both sides offering -110 odds, showcasing the potential for a high-scoring affair. These odds provide valuable insights for bettors looking to make informed decisions.
Given the teams' recent performances, the Bills are expected to leverage their strong defense, while the Patriots aim to counter with strategic plays. For those keen on betting, Caesars offers some of the best odds available. Ready to take your betting game to the next level? Start your OddsTrader Turbo subscription today or place your bet with a U.S. regulated sportsbook.
Explore more about the NFL and make smarter bets by visiting our NFL odds page. Whether you're a seasoned bettor or a newbie, these insights are designed to help you make the most of your wagers.
Spread (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
New EnglandSpread
-1.4%
EV
-1.4%
BuffaloSpread
-0.9%
EV
-0.9%
MONEYLINE (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
New EnglandMONEYLINE
+3.0%
EV
+3.0%
BuffaloMONEYLINE
-6.7%
EV
-6.7%
Total (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
OVERTotal
-9.9%
EV
-9.9%
UNDERTotal
+5.8%
EV
+5.8%
Spread (1H)
BEST LINE
New EnglandSpread
BuffaloSpread
MONEYLINE (1H)
BEST LINE
New EnglandMONEYLINE
BuffaloMONEYLINE
Total (1H)
BEST LINE
OVERTotal
UNDERTotal
Spread (2H)
BEST LINE
New EnglandSpread
BuffaloSpread
MONEYLINE (2H)
BEST LINE
New EnglandMONEYLINE
BuffaloMONEYLINE
Total (2H)
BEST LINE
OVERTotal
UNDERTotal
Spread (1Q)
BEST LINE
New EnglandSpread
BuffaloSpread
MONEYLINE (1Q)
BEST LINE
New EnglandMONEYLINE
BuffaloMONEYLINE
Total (1Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (2Q)
BEST LINE
New EnglandSpread
BuffaloSpread
MONEYLINE (2Q)
BEST LINE
New EnglandMONEYLINE
BuffaloMONEYLINE
Total (2Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (3Q)
BEST LINE
New EnglandSpread
BuffaloSpread
MONEYLINE (3Q)
BEST LINE
New EnglandMONEYLINE
BuffaloMONEYLINE
Total (3Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (4Q)
BEST LINE
New EnglandSpread
BuffaloSpread
MONEYLINE (4Q)
BEST LINE
New EnglandMONEYLINE
BuffaloMONEYLINE
Total (4Q)
BEST LINE
OVERTotal
UNDERTotal
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