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FINAL
Nov 16, 2025 1:00 PM EST
TB 32 vs BUF 44
Week 11
BUF
-6½ (-115)o45½ (-107)
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Tampa Bay Buccaneers vs Buffalo Bills Odds
Updated:Nov 16, 2025 1:56 AM EST
The upcoming NFL showdown on November 16, 2025, features the Tampa Bay Buccaneers visiting the Buffalo Bills at Highmark Stadium in Orchard Park, NY. This Sunday football game, broadcast on CBS, promises an exciting clash between two talented teams in the 2025-26 NFL season. The current odds favor the Buffalo Bills with a point spread of -6 -112, compared to the Buccaneers at +6 -110, reflecting a strong home advantage for the Bills. Opening odds started at a similar spread, indicating steady confidence in Buffalo's performance.
Understanding the betting lines and point spread is crucial for making smart wagers. The over-under total is set at 46.5, with the over at -114 and under at -107, suggesting a moderately high-scoring game. Bettors can leverage these insights and compare the latest odds with the opening lines to identify value bets and potential market movements.
For those looking to dive deeper, our NFL odds page offers comprehensive betting odds and trends. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. The best odds today for Buffalo Bills are -6 -112 at Caesars, and for Tampa Bay Buccaneers +6 -110 at Caesars.
Spread (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
Tampa BaySpread
+1.1%
EV
+1.1%
BuffaloSpread
-6.7%
EV
-6.7%
MONEYLINE (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
Tampa BayMONEYLINE
+7.4%
EV
+7.4%
BuffaloMONEYLINE
-8.9%
EV
-8.9%
Total (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
OVERTotal
-3.4%
EV
-3.4%
UNDERTotal
+1.0%
EV
+1.0%
Spread (1H)
BEST LINE
Tampa BaySpread
BuffaloSpread
MONEYLINE (1H)
BEST LINE
Tampa BayMONEYLINE
BuffaloMONEYLINE
Total (1H)
BEST LINE
OVERTotal
UNDERTotal
Spread (2H)
BEST LINE
Tampa BaySpread
BuffaloSpread
MONEYLINE (2H)
BEST LINE
Tampa BayMONEYLINE
BuffaloMONEYLINE
Total (2H)
BEST LINE
OVERTotal
UNDERTotal
Spread (1Q)
BEST LINE
Tampa BaySpread
BuffaloSpread
MONEYLINE (1Q)
BEST LINE
Tampa BayMONEYLINE
BuffaloMONEYLINE
Total (1Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (2Q)
BEST LINE
Tampa BaySpread
BuffaloSpread
MONEYLINE (2Q)
BEST LINE
Tampa BayMONEYLINE
BuffaloMONEYLINE
Total (2Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (3Q)
BEST LINE
Tampa BaySpread
BuffaloSpread
MONEYLINE (3Q)
BEST LINE
Tampa BayMONEYLINE
BuffaloMONEYLINE
Total (3Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (4Q)
BEST LINE
Tampa BaySpread
BuffaloSpread
MONEYLINE (4Q)
BEST LINE
Tampa BayMONEYLINE
BuffaloMONEYLINE
Total (4Q)
BEST LINE
OVERTotal
UNDERTotal
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