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The upcoming face-off between the Dallas Cowboys and San Francisco 49ers promises to be a thrilling encounter at Levi's Stadium in Santa Clara, CA. Scheduled for October 27, 2024, at 20:20 ET, this game is set to be broadcast live on NBC. The 49ers have shown dominance in their recent matchups against the Cowboys, including a decisive victory on October 8th, 2023 with a final score of 42-10. This season, the Cowboys have struggled on the road with a 2-4-0 against the spread (ATS) record, while the 49ers have maintained a balanced 3-4-0 ATS record at home. You can find more details on their ATS records on our NFL standings page. The 49ers are favored with a -4 point spread, and both teams have a history of surpassing the projected total points, which currently stands at 47.
For bettors, the starting quarterbacks are pivotal; Dak Prescott leads the Cowboys, while Brock Purdy is expected to start for the 49ers. Injuries could impact the game significantly, with key players like Christian McCaffrey and Brandon Aiyuk on the injured reserve list. The Cowboys' defense, ranked top in several categories, will need to counter the 49ers' offensive prowess, which averages 404.286 total yards per game. With the 49ers' home advantage and the Cowboys' inconsistent away performance, this matchup is poised to be a strategic battle on the field.