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FINAL
Sep 28, 2025 4:05 PM EDT
IND 20 vs LA 27
Week 4
LA
-3½ (-108)o49½ (-110)
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Betting Trends: Indianapolis Colts vs L.A. Rams
Updated:Sep 28, 2025 2:47 AM EDT
The Indianapolis Colts are set to face off against the L.A. Rams on September 28, 2025, at SoFi Stadium in Inglewood, CA, with the game airing on FOX. This exciting NFL matchup promises thrilling action, with the Colts' quarterback Daniel Jones leading the charge against the Rams' formidable defense. Jones has been impressive, helping the Colts maintain a perfect 3-0 record against the spread, as highlighted on our NFL standings page. Meanwhile, the Rams, led by Matthew Stafford, will look to leverage their passing game.
With the Colts' strong pass offense averaging 265.3 yards per game against the Rams' pass defense, which allows 165.3 yards, expect a high-scoring affair. The betting odds show the Rams as favorites with a -3.5 point spread, but the Colts have proven to be resilient underdogs. The total points line is set at 49.5, suggesting a potentially high-scoring game.
In their last matchup on October 1, 2023, the Rams edged out the Colts 29-23, going over the 44.5 point total. Betting insights suggest a close game with potential for high scores. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
ATS Records
All
9-8 (10th)Against the Spread12-8 (7th)
8-9 (18th)Straight Up14-6 (5th)
-4.7Straight Up Units-1.0
9-8Over / Under12-8
TEAM MATCHUP
OFF
DEF
OFF
DEF
27.4Points30.5
14.8First Half15.1
12.7Second Half15.4
6.4First Quarter6.7
8.4Second Quarter8.5
6.4Third Quarter7.3
5.9Fourth Quarter7.7
345.9Total Yards394.6
6Yards Per Play6.2
227.8Passing Yards268.1
21.2 - 32.2 (65.8%)Completions-Attempts22.8 - 35.2 (64.9%)
6.7Yards Per Passing Play7.3
1.7 (12)Sacks (Yards)1.4 (9)
118.1Rushing Yards126.6
26Attempts27.4
4.5Yards Per Rush4.6
20.71st Downs23.3
11.7Passing13.9
7.2Rushing7.4
1.8Penalties2
4.9 / 11.5 (42.6%)3rd Down4.5 / 11.3 (39.6%)
1.1 / 1.6 (66.7%)4th Down1.2 / 1.8 (66.7%)
2.5 / 3.9 (65.2%)Red Zone2.8 / 4.5 (63.2%)
6.1 (51.2)Penalties (Yards)4.4 (33.7)
1.4Turnovers1.4
0.8Interceptions0.9
0.5Fumbles Lost0.4
59.9Total Plays63.9
5.9Kickoffs6.1
3.9Returns3.5
113.4Return Yards87
28.8Yards Per Return25.1
2.6Punts2.9
1.3Returns1.6
11.8Return Yards15.2
9.1Yards Per Return9.3
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