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Get ready for an electrifying Monday night football clash on October 6, 2025, as the Kansas City Chiefs take on the Jacksonville Jaguars at EverBank Stadium in Jacksonville, FL. This NFL showdown promises to deliver excitement and strategic plays, drawing viewers to their screens on ABC/ESPN. The Chiefs, renowned for their offensive prowess, face the Jaguars, who are eager to capitalize on their home advantage. Our picks suggest a Kansas City victory with a predicted score of 25-20, favoring the Chiefs on the -3.5 spread. Historically, our predictions have been spot-on, boasting a solid hit rate in recent games. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. For more insights, check out our NFL picks page.
Seattle - -3½ -110BetOnline | |||||||
![]() L.A. Rams - -3 -120Bovada | |||||||
Jacksonville - -7½ -101Bet105 | |||||||
![]() Cincinnati - -3½ -102Bet105 | |||||||
![]() Indianapolis - +3½ -110BetOnline | |||||||
![]() Pittsburgh - -2½ -122Bet105 | |||||||
![]() Houston - +1½ -120Bovada | |||||||
Carolina - +2½ -102Bet105 | |||||||
![]() Tennessee - -2½ -110Bookmaker | |||||||
Detroit - -7 -105Bet105 | |||||||
![]() L.A. Chargers - -10 -115Bookmaker | |||||||
![]() Las Vegas - -3 -120BetOnline | |||||||
Philadelphia - -4 -103Bet105 | |||||||
Minnesota - +1½ -115Bovada | |||||||
![]() N.Y. Giants - +3 -110MyBookie | |||||||
![]() Kansas City - -2½ -110MyBookie |