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Before the anticipated clash on September 28, 2025, between the Jacksonville Jaguars and San Francisco 49ers, NFL fans are gearing up for a thrilling Sunday football game at Levi's Stadium in Santa Clara, CA. The 49ers have shown a strong pass offense, while the Jaguars' pass defense aims to counter with strategic plays. The market is buzzing with player props, especially focusing on Christian McCaffrey's rushing yards. Our projections suggest McCaffrey (OVER 121.5) has a 64.8% hit rate, offering bettors a promising EV. Brock Purdy's passing yards are also under the spotlight, projected to exceed 261.5 yards with a 62.4% hit rate. For those seeking more insights, check out our NFL player props page. Tune in to FOX for live coverage and get ready to place your bets with a U.S. regulated sportsbook or Start your OddsTrader Turbo subscription today!