Floyd Mayweather Jr. is set to take on Manny Pacquiao in a bout between two boxing legends. It’s a rematch of their first fight, which happened back on May 2, 2015. Mayweather ended up winning by unanimous decision, so it will be interesting to see what happens this time around.
Mayweather vs. Pacquiao Rematch will take place on September 19, 2026 at the iconic Sphere in Las Vegas. We saw UFC 306 held here to great success, as it’s a more engaging environment due to the vibrant visuals. It just adds another layer of prestige to this fight between two of the best boxers of all-time.
Mayweather comes in as a relatively high favorite in this fight vs. Pacquiao. The biggest question here is, can Pacquiao hand Mayweather the first loss of his career? Read on to find out our full breakdown of Mayweather vs. Pacquiao Rematch.
Mayweather vs. Pacquiao Rematch Details
As mentioned above, the Mayweather vs. Pacquiao Rematch takes place on September 19, 2026, at The Sphere in Las Vegas. This match will be streamed globally on Netflix, marking the fifth boxing match to be shown here. Previous bouts were Jake Paul vs. Anthony Joshua, Jake Paul vs. Mike Tyson, Katie Taylor vs. Amanda Serrano III, and Canelo Alvarez vs. Terence Crawford.
Mayweather vs. Pacquiao is expected to be a welterweight fight that goes 12 rounds. It’s impressive to see both Mayweather (49 years old) and Pacquiao (47 years old) in a 12-round fight despite their advanced age.
On another note, it will be interesting to see how much these fighters will be affected by their long layoffs. Mayweather plans to have a tune-up fight prior to this one, ending his nine-year retirement by facing none other than fellow legend Mike Tyson in an exhibition this spring.
Meanwhile, Pacquiao has already returned from his four-year retirement, fighting then-WBC welterweight champion Mario Barrios to a majority draw. Before this bout vs. Mayweather, Pacquiao will fight former welterweight champion Ruslan Provodnikov on April 18th.
Will Mayweather’s rust put him at a disadvantage vs. Pacquiao? It’s something to think about.
Mayweather vs. Pacquiao Rematch Opening Lines
Boxing betting odds for Mayweather vs. Pacquiao Rematch are courtesy of BetOnline Sportsbook as of Tuesday, February 24 at 3:00 p.m. ET.
- Moneyline: Mayweather -240 / Pacquiao +181
Mayweather comes in as a -240 favorite, which means you’d be risking $240 to win $100 if you bet on him to win. If you back Pacquiao, you win $181 on a $100 wager. It’s not surprising to see Mayweather boxing odds have him as a favorite, especially with his undefeated record.
It’s worth noting that unlike other sports like football or baseball, -240 doesn’t always equate to being a massive favorite in the world of boxing.
For context, this line is similar to what we saw with Mayweather vs. Pacquiao back in 2015. In that match, Mayweather’s odds ranged from -210 to -250, depending on the sportsbook.
Mayweather vs. Pacquiao Rematch Prediction
When I’m trying to make a Mayweather vs. Pacquiao 2 prediction, there’s one thing that I keep asking myself. Do I really think that Mayweather was going to risk coming out of retirement to lose his undefeated career record? This is a legend who initially called it a quits with a 50-0 record.
Mayweather is like a calculated fighter who carefully chooses his fights. I doubt that he gets his first career loss in his 51st bout. The goal here seems to create a global spectacle against his old rival in Pacquiao.
While Pacquiao’s team recently told ESPN that this a legit fight, not an exhibition, we have to call this like we see it: it feels like an opportunity for two legends to capitalize on having a fight on a global streaming platform like Netflix.
With that in mind, the play here is to ride with Mayweather, even at -240 odds. I know that it can feel uncomfortable to lay this much juice, but this feels like the right side. Once more props open up, you can sprinkle “Mayweather to win by decision” for a better price. It’s unlikely that he knocks out Pacquiao, especially since decision was the result of their first match.
Prediction: Mayweather by decision. It’ll be a fight that looks close, but Mayweather squeaks it out with his trademark patient approach. Despite Pacquiao boxing odds showing nice value, drink the juice with Mayweather here.
Mayweather vs. Pacquiao Rematch Already Drawing Criticism
One of the biggest criticisms with modern-day boxing is that it’s become more of a spectacle than a competition. No fight encapsulates that thought better than Jake Paul vs. Mike Tyson, which took place back in November 2024.
While Mayweather vs. Pacquiao 2 isn’t to the same degree as Paul vs. Tyson, since the latter was 58 years old at the time of the bout, it’s still drawing some criticism.
A recent BBC article highlighted how this fight is the latest “ego-driven sparring session” on Netflix. Honestly, it’s hard to disagree too much here. That’s exactly what it feels like.
But even still, it’s hard not to watch two legends with a storied history return to the ring. I’m excited to watch this fight and plan to bet on Mayweather moneyline at -240 odds. It’s good to be hyped up for a fight between legends, and that’s exactly the case here.
Best Boxing Sportsbooks to Bet on Mayweather vs. Pacquiao Rematch
When it comes to betting on major boxing events like Mayweather vs. Pacquiao Rematch, choosing the right sportsbook can make a big difference in your overall experience and potential payouts. Some books offer deeper markets, more competitive lines, and better betting tools. Three sportsbooks consistently recommended by experienced bettors for high-profile boxing matches are BetOnline, Bovada, and BookMaker.
BetOnline stands out for its comprehensive fight markets and early odds releases. If you want access to multiple moneyline options, round props, method of victory bets, and round-by-round over/unders, BetOnline typically posts them sooner than most competitors.
Bovada is another top choice for Mayweather vs. Pacquiao Rematch betting. Bovada’s boxing odds are widely referenced across forums and pick guides, and its platform often features competitive pricing on the moneyline and popular props like total rounds and round scoring.
BookMaker also deserves mention for its flexibility and higher limits. Many serious boxing bettors prefer BookMaker because it allows larger stakes on fight nights and its props tend to be creative and deep.
Mayweather vs Pacquiao Rematch FAQs
What is the official date for Mayweather vs. Pacquiao Rematch?
Mayweather vs. Pacquiao Rematch is set for September 19, 2026, at the Sphere in Las Vegas. Officials have not yet confirmed the final weight class or the total number of rounds for the bout.
Who is the betting favorite in Mayweather vs. Pacquiao Rematch?
Floyd Mayweather Jr. is a -240 favorite at BetOnline, while Pacquiao is a +181 underdog.
Will Mayweather vs. Pacquiao Rematch stream on Netflix?
Yes. The rematch will air live worldwide on Netflix. It will mark the first boxing event hosted at the Sphere and ranks among Netflix’s most high-profile live sports broadcasts to date.
Where can I place bets on Mayweather vs. Pacquiao Rematch?
The fight will be available at leading licensed sportsbooks offering boxing odds and prop markets. OddsTrader.com provides updated sportsbook ratings, early betting lines, available props, and current sign-up bonuses.
How old are Mayweather and Pacquiao for the rematch?
Mayweather will be 49 years old on fight night, while Pacquiao will be 47. Their combined age of 96 makes this one of the oldest marquee matchups in modern boxing history, regardless of the finalized weight class.
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*The line and/or odds referenced in this article might have changed since the content was published. For the latest information on line movements, visit OddsTrader’s free betting odds tool.