Sep 30, 2025 1:08 PM EDTGame 1

Cleveland

(R) G. Williams

DET

-165o6 (-115)

ESPN, ESPN Networks

MATCHUP PREDICTION ODDS BOOSTS PLAYER PROPS GAME PROPS INJURIES WEATHER

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Detroit Tigers vs Cleveland Guardians Odds

Updated:Sep 30, 2025 2:09 AM EDT

Get ready for an exciting matchup as the Detroit Tigers take on the Cleveland Guardians on September 30, 2025, at Progressive Field in Cleveland, OH. This MLB showdown is set to thrill baseball fans and sports bettors alike, with the Tigers entering as favorites. The game kicks off at 1:08 PM and will be broadcasted on ESPN, offering ample opportunity for fans to catch all the action live.

The betting odds have been dynamic, with the Tigers opening at -165 on the moneyline, indicating strong confidence from the bookmakers in their victory. Meanwhile, the Guardians, with odds of +140, are seen as the underdog but could offer great value for bettors seeking an upset. The run line is set at -1.5 for the Tigers at +118, and +1.5 for the Guardians at -140, providing intriguing options for those looking to bet on the point spread.

Additionally, the over/under is set at 6.0 runs, with the over priced at -115 and the under at -105, giving bettors a chance to wager on the total score. Understanding these betting lines and odds can provide valuable insights for making informed bets. For more detailed odds and insights, check out the MLB odds page

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Where is the Tigers vs Guardians game being played?

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ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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Personalize your notifications and get updates on the teams, players or events you care about most. TUE 09/301:08 PMGame 1 DETT. Skubal (L) 87-75 78% -164FanDuel
CLEG. Williams (R) 88-74 22% +140Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. TUE 09/303:08 PMGame 1 SDN. Pivetta (R) 90-72 17% -102FanDuel
CHCM. Boyd (L) 92-70 83% -115Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. TUE 09/306:08 PMGame 1 BOSG. Crochet (L) 89-73 25% +115Caesars
NYYM. Fried (L) 94-68 75% -134FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. TUE 09/309:08 PMGame 1 CINH. Greene (R) 83-79 25% +175Bet365
LADB. Snell (L) 93-69 75% -196FanDuel

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