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Get ready for an electrifying NBA showdown as the Cleveland Cavaliers take on the New York Knicks on October 22, 2025, at the iconic Madison Square Garden in New York, NY. This much-anticipated clash will be broadcast live on ESPN, offering fans a thrilling encounter. With both teams eager to kick off their season with a win, this game promises high stakes and intense competition. The Cavaliers, led by their dynamic duo, will look to leverage their recent form, having shown strong performances against top-tier teams. Meanwhile, the Knicks are set to capitalize on their home advantage, with their star players aiming to outshine their opponents. Betting trends indicate a close contest, with the Knicks favored at -4 according to Caesars. Smart bettors should consider the Knicks' solid home record, which is available on our NBA standings page. This matchup also highlights key player performances, with the Cavaliers' 3-point shooting being a crucial factor. The odds spread and total points are pivotal for betting strategies, as the game stats suggest a potential high-scoring affair. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
Oklahoma City - -6½ -105Caesars | |||||||
L.A. Lakers - -3½ -110Caesars | |||||||
New York - -4 -110Caesars | |||||||
Charlotte - -3 -110BetRivers | |||||||
![]() Orlando - -7 -110Caesars | |||||||
![]() Atlanta - -5½ -115BetMGM | |||||||
Boston - -1½ -115BetMGM | |||||||
Chicago - +2½ -110Caesars | |||||||
![]() Memphis - -6 -110Caesars | |||||||
Milwaukee - -8 -110Caesars | |||||||
![]() Utah - +8 -110BetRivers | |||||||
Dallas - +1 -115BetRivers | |||||||
Phoenix - -1 -115Caesars | |||||||
![]() Portland - +2½ -110Caesars | |||||||
![]() Indiana - +7 -110Caesars | |||||||
![]() Golden State - -1 -110Caesars |
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