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The Iowa State Cyclones are set to face off against the Colorado Buffaloes on October 11, 2025, at Folsom Field in Boulder, CO. The Cyclones are coming in strong with notable players like the defensive back Jontez Williams out due to a knee injury, which could impact their defensive strategy. Meanwhile, the Buffaloes are dealing with multiple injuries, including key players like Simeon Price, who is out with an ankle injury. These injuries are crucial for bettors to consider when placing their bets on this NCAAF matchup. With the game airing on ESPN, fans and bettors alike will have their eyes glued to this Saturday football showdown. For more detailed player statuses, visit our NCAAF injuries page using this link. Ready to make smarter bets? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and gain the edge.
![]() Middle Tennessee 1-4- +2½ -105FanDuel | |||||||
![]() UTEP 1-4- +2½ -108FanDuel | |||||||
![]() Kennesaw State 3-2- +5½ -104FanDuel | |||||||
Tulane 4-1- -7½ -102FanDuel | |||||||
![]() Sam Houston State 0-5- +10 -109BetRivers | |||||||
![]() Georgia Southern 2-3- -1½ -105FanDuel | |||||||
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![]() Washington 4-1- -9½ -115FanDuel | |||||||
#18Florida State 3-2- -9½ -110FanDuel | |||||||
Army 2-3- - | |||||||
Michigan State 3-2- -4½ -115FanDuel | |||||||
![]() #19Missouri 5-0- +5½ -110FanDuel | |||||||
![]() Akron 2-4- - | |||||||
Oklahoma State 1-4- +9½ -115FanDuel | |||||||
#22Illinois 5-1- +15½ -105FanDuel | |||||||
![]() James Madison 4-1- - | |||||||
Bowling Green 2-3- - | |||||||
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SMU 3-2- -20½ -115FanDuel | |||||||
![]() #4Ole Miss 5-0- -33½ -115FanDuel | |||||||
Eastern Michigan 1-5- - | |||||||
![]() Kent State 1-4- - | |||||||
![]() Western Michigan 3-3- - | |||||||
![]() Colorado 2-4- +4½ -110FanDuel | |||||||
Maryland 4-1- +6½ -108FanDuel | |||||||
#21Notre Dame 3-2- -22½ -110FanDuel | |||||||
![]() #7Penn State 3-2- -20½ -110FanDuel | |||||||
![]() #2Oregon 5-0- -9½ -115FanDuel | |||||||
UNLV 5-0- - | |||||||
![]() #17Georgia Tech 5-0- -15½ -115FanDuel | |||||||
![]() #9Texas 3-2- -3½ -112FanDuel | |||||||
Marshall 2-3- - | |||||||
![]() Oregon State 0-6- - | |||||||
Georgia State 1-4- - | |||||||
![]() Kansas State 2-4- +1½ -118FanDuel | |||||||
Temple 3-2- - | |||||||
#15Tennessee 4-1- -12½ -112BetRivers | |||||||
![]() Florida Atlantic 2-3- - | |||||||
Wyoming 2-3- - | |||||||
![]() Wisconsin 2-3- +3½ -122FanDuel | |||||||
![]() Coastal Carolina 2-3- - | |||||||
#6Texas A&M 5-0- -7½ -115FanDuel | |||||||
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Auburn 3-2- +6½ -110BetMGM | |||||||
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USC 4-1- +1½ -110BetMGM | |||||||
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Minnesota 3-2- -9½ -115FanDuel | |||||||
#13LSU 4-1- -10½ -110FanDuel | |||||||
![]() Arizona 4-1- +1½ -105FanDuel | |||||||
Texas State 3-2- - | |||||||
![]() Boise State 3-2- - | |||||||
![]() Utah 4-1- -4½ -112FanDuel | |||||||
![]() Nevada 1-4- - | |||||||
![]() Hawaii 4-2- -2½ -105FanDuel |
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