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As the countdown to October 11, 2025, begins, football enthusiasts are in for a treat with the Iowa State Cyclones facing off against the Colorado Buffaloes at Folsom Field in Boulder, CO. This Saturday football clash promises to be a spectacle, broadcasted on ESPN, and is part of the exhilarating NCAAF season. The Cyclones, known for their strategic plays, will be looking to assert dominance against the Buffaloes, who boast a solid home record.
Our prediction model gives the Cyclones the edge, projecting a final score of 27-24 in their favor. Bettors should note that picking Iowa State on the moneyline could be a smart move with their recent performance showing a 63.2% hit rate in similar matchups. Historically, our predictions have been profitable, with a strong record in point spread bets, boasting a 6-4 record in the last 10 games. This high EV prediction offers an opportunity for savvy bettors to capitalize.
For those looking to make informed bets, check out our detailed NCAAF picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. Don't miss out on this chance to engage with Saturday football at its finest!
![]() Middle Tennessee 1-4- +2½ -105FanDuel | |||||||
![]() UTEP 1-4- +2½ -108FanDuel | |||||||
![]() Kennesaw State 3-2- +5½ -104FanDuel | |||||||
Tulane 4-1- -7½ -102FanDuel | |||||||
![]() Sam Houston State 0-5- +10 -109BetRivers | |||||||
![]() Georgia Southern 2-3- -1½ -105FanDuel | |||||||
![]() North Texas 5-0- +1½ -115FanDuel | |||||||
![]() Colorado State 1-4- +5½ -110FanDuel | |||||||
![]() Washington 4-1- -9½ -115FanDuel | |||||||
#18Florida State 3-2- -9½ -110FanDuel | |||||||
Army 2-3- -14½ -110FanDuel | |||||||
Michigan State 3-2- -4½ -115FanDuel | |||||||
![]() #19Missouri 5-0- +5½ -110FanDuel | |||||||
![]() Akron 2-4- - | |||||||
Oklahoma State 1-4- +9½ -115FanDuel | |||||||
#22Illinois 5-1- +15½ -105FanDuel | |||||||
![]() James Madison 4-1- - | |||||||
Bowling Green 2-3- - | |||||||
![]() Cincinnati 4-1- -9½ -110FanDuel | |||||||
SMU 3-2- -20½ -115FanDuel | |||||||
![]() #4Ole Miss 5-0- -33½ -115FanDuel | |||||||
Eastern Michigan 1-5- - | |||||||
![]() Kent State 1-4- - | |||||||
![]() Western Michigan 3-3- - | |||||||
![]() Colorado 2-4- +4½ -110FanDuel | |||||||
Maryland 4-1- +6½ -108FanDuel | |||||||
#21Notre Dame 3-2- -22½ -110FanDuel | |||||||
![]() #7Penn State 3-2- -20½ -110FanDuel | |||||||
![]() #2Oregon 5-0- -9½ -115FanDuel | |||||||
UNLV 5-0- - | |||||||
![]() #17Georgia Tech 5-0- -15½ -115FanDuel | |||||||
![]() #9Texas 3-2- -3½ -112FanDuel | |||||||
Marshall 2-3- - | |||||||
![]() Oregon State 0-6- +6½ -115FanDuel | |||||||
Georgia State 1-4- - | |||||||
![]() Kansas State 2-4- +1½ -118FanDuel | |||||||
Temple 3-2- - | |||||||
#15Tennessee 4-1- -12½ -112BetRivers | |||||||
![]() Florida Atlantic 2-3- - | |||||||
Wyoming 2-3- -1½ -104FanDuel | |||||||
![]() Wisconsin 2-3- +3½ -122FanDuel | |||||||
![]() Coastal Carolina 2-3- - | |||||||
#6Texas A&M 5-0- -7½ -115FanDuel | |||||||
![]() UTSA 2-3- - | |||||||
Auburn 3-2- +6½ -110BetMGM | |||||||
![]() #11Texas Tech 5-0- -11½ -110FanDuel | |||||||
USC 4-1- +1½ -110BetMGM | |||||||
![]() Boston College 1-4- +14½ -122FanDuel | |||||||
Minnesota 3-2- -9½ -115FanDuel | |||||||
#13LSU 4-1- -10½ -110FanDuel | |||||||
![]() Arizona 4-1- +1½ -105FanDuel | |||||||
Texas State 3-2- - | |||||||
![]() Boise State 3-2- -16½ -110FanDuel | |||||||
![]() Utah 4-1- -4½ -112FanDuel | |||||||
![]() Nevada 1-4- - | |||||||
![]() Hawaii 4-2- -2½ -105FanDuel |
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