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Our betting trends data and game stats shine a light on the Saturday football matchup on October 18, 2025, when the Oklahoma Sooners visit Williams-Brice Stadium in Columbia, SC, to face the South Carolina Gamecocks. Kickoff is slated for 12:45 PM ET on sec network and espn networks. The Sooners (5-1 SU, 3-3 ATS) boast an offense averaging 266.7 passing yards and 122.3 rushing yards per game, while their defense allows just 126.3 passing yards and 84.8 rushing yards. South Carolina (3-3 SU, 3-3 ATS) counters with 194.7 passing yards and 115.3 rushing yards but yields 192.5 through the air and 147.0 on the ground.
Pass offense vs pass defense clearly favors Oklahoma’s aerial attack against South Carolina’s secondary. In the ground game, the Sooners’ 122.3 rushing yards per contest match up well against the Gamecocks’ 147.0 rushing yards allowed. Oklahoma’s offensive line permits only 2.17 sacks per game while recording 3.67 sacks on defense, giving the Sooners the upper hand in pass protection vs pass rush.
At Caesars, Oklahoma enters as a 5.5-point favorite with a 43-point total. The under has hit in none of Oklahoma’s contests and two of South Carolina’s three games, highlighting another angle for bettors. Check current ATS standings on our NCAAF standings page.
In their October 19, 2024 meeting, South Carolina downed Oklahoma 35-9. Both teams report no major injuries, and starting quarterbacks are set to be confirmed, though each side is expected to field its primary signal-caller. With Oklahoma’s balanced attack and elite defense, lean toward the Sooners covering the 5.5 spread.
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![]() Sam Houston State 0-663% +2½ -104FanDuel | |||||||
East Carolina 3-359% -17 -109BetRivers | |||||||
![]() #2Miami (FL) 5-040% -13½ -110Caesars | |||||||
Minnesota 4-240% +8½ -112FanDuel | |||||||
![]() Utah State 3-326% -3½ -104FanDuel | |||||||
![]() California 4-235% -9½ -118BetRivers | |||||||
Miami (OH) 3-30% -12½ -115FanDuel | |||||||
![]() Boston College 1-577% -1½ -110Bet365 | |||||||
![]() Duke 4-281% -1½ -110Caesars | |||||||
Bowling Green 3-333% -3½ -115FanDuel | |||||||
![]() #17Vanderbilt 5-157% -2½ -110Caesars | |||||||
![]() Michigan 4-255% -5½ -115BetMGM | |||||||
![]() Houston 5-150% +1½ -115BetMGM | |||||||
TCU 4-250% -2½ -120FanDuel | |||||||
![]() Tulane 5-122% -9½ -110Bet365 | |||||||
![]() South Carolina 3-380% +6 -117SugarHouse | |||||||
UCF 3-327% -7 -115BetMGM | |||||||
![]() Toledo 3-340% -26½ -110Caesars | |||||||
![]() Massachusetts 0-6100% +17½ -118BetMGM | |||||||
![]() Louisiana-Monroe 3-3100% +6½ -110BetRivers | |||||||
![]() Northwestern 4-230% -3 -115Bet365 | |||||||
Appalachian State 4-20% -10½ -105FanDuel | |||||||
![]() Ohio 3-30% -11 -110Caesars | |||||||
![]() James Madison 5-127% -1½ -105BetMGM | |||||||
![]() Charlotte 1-5100% +11½ -110Caesars | |||||||
![]() Clemson 3-325% -8½ -110FanDuel | |||||||
![]() #3Indiana 6-024% -26½ -115BetMGM | |||||||
Marshall 3-367% +3 -114BetRivers | |||||||
Ball State 2-40% -1½ +100BetMGM | |||||||
![]() Boise State 4-267% -11½ -110BetMGM | |||||||
![]() North Texas 5-130% -4 -110Caesars | |||||||
![]() #9Georgia 5-153% -7 -115BetMGM | |||||||
![]() Arkansas 2-480% +8 -115SugarHouse | |||||||
![]() Wisconsin 2-495% +26½ -110FanDuel | |||||||
Air Force 1-540% -3½ -115FanDuel | |||||||
UAB 2-425% +21½ -110Caesars | |||||||
![]() Arizona State 4-239% +9½ -110Caesars | |||||||
Florida 2-436% -8½ -113BetRivers | |||||||
![]() Louisiana 2-467% +4 -113BetRivers | |||||||
![]() #18Virginia 5-10% -17 -105Caesars | |||||||
Rutgers 3-3100% +17½ -115FanDuel | |||||||
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![]() Colorado State 2-460% -2½ -110Bet365 | |||||||
UCLA 2-433% -3½ -102BetMGM | |||||||
Iowa 4-280% -2½ -118FanDuel | |||||||
Kentucky 2-375% +13 -112BetRivers | |||||||
![]() #19South Florida 5-10% -21½ -110Caesars | |||||||
Syracuse 3-329% +11½ -115BetMGM | |||||||
#13Notre Dame 4-261% -9 -110Caesars | |||||||
#6Alabama 5-130% -8 -110Caesars | |||||||
Auburn 3-365% +2 -114BetRivers | |||||||
Oklahoma State 1-587% +22 -109BetRivers | |||||||
#15Brigham Young 6-056% +3½ -110BetMGM | |||||||
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![]() Oregon State 0-7- -20½ -110FanDuel | |||||||
Stanford 2-475% +18 -110Caesars | |||||||
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