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The upcoming NFL regular season Week 15 matchup on December 14, 2025, features the Arizona Cardinals taking on the Houston Texans at the NRG Stadium in Houston, TX. This game is a must-watch for fans and bettors alike, airing on Fox. With the Houston Texans favored at -9½ -110 against the Cardinals, who hold an underdog spread of +9½ -109, the betting lines indicate a clear edge for Houston. The over/under is set at 42½ with the under favored at -113, suggesting a potentially defensive battle.
Opening odds showed Houston as favorites as well, but the current line movement reflects bettors' growing confidence in the Texans maintaining their home advantage. These odds and betting lines are crucial for making informed wagers, allowing bettors to gauge market sentiment and potential value. The Cardinals will need to overcome the Texans' strong home presence to upset the spread.
For those looking to dive deeper, the NFL odds page provides comprehensive details on all NFL betting markets. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Tampa Bay 7-637% -4 -110Bet365 | |||||||
![]() Houston 8-517% -9½ -110Caesars | |||||||
Philadelphia 8-519% -10½ -110Bet365 | |||||||
Jacksonville 9-426% -11½ -112BetRivers | |||||||
![]() Chicago 9-47% -7½ -110Caesars | |||||||
New England 11-253% +1½ -115FanDuel | |||||||
![]() Cincinnati 4-933% +2½ -105FanDuel | |||||||
![]() Kansas City 6-765% -4½ -110Bet365 | |||||||
![]() N.Y. Giants 2-1145% -2 -110Bet365 | |||||||
Seattle 10-311% -13½ -109Caesars | |||||||
Denver 11-218% +2½ -110Caesars | |||||||
New Orleans 3-1055% +3 -121SugarHouse | |||||||
![]() L.A. Rams 10-350% -5½ -110Bet365 | |||||||
![]() San Francisco 9-47% -12½ -110Bet365 | |||||||
Dallas 6-6-130% -5½ -110Bet365 | |||||||
![]() Pittsburgh 7-635% -3½ -105Bet365 |
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