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The Arizona Cardinals will face off against the L.A. Chargers Chargers at the State Farm Stadium in Glendale, AZ, on October 21, 2024, at 9:00 PM EST. The Chargers are currently favored with a -1.5 point spread according to Caesars, and fans can catch the action live on ESPN+. The last time these two teams met, the Chargers edged out the Cardinals with a final score of 25-24 on November 27, 2022. Check out the full details of that game in our last matchup. The Cardinals, led by starting quarterback Kyler Murray, will look to improve their home ATS record of 1-2. Meanwhile, Justin Herbert will lead the Chargers, who boast a 2-1 ATS away record. For more ATS standings, visit our NFL standings page. With the Cardinals' current offensive struggles and the Chargers' strong defensive stats, bettors might find value in the under 44 points, which has hit in four of the Chargers' last five games.
PRIORITY
 Tennessee 0-274% +4½ -118FanDuel | |||||||
 Carolina 0-280% +5½ -109BetRivers | |||||||
 Washington 1-132% -3½ +100Caesars | |||||||
 Cleveland 0-277% +8 -110BetMGM | |||||||
 Minnesota 1-146% -2½ -130BetMGM | |||||||
 Philadelphia 2-044% -3 -125Caesars | |||||||
 New England 1-164% +1½ -105Caesars | |||||||
 Tampa Bay 2-018% -6½ -110FanDuel | |||||||
 Jacksonville 1-162% -1½ -110Bet365 | |||||||
 L.A. Chargers 2-028% -2½ -114BetRivers | |||||||
 Seattle 1-123% -7½ -105Bet365 | |||||||
 Chicago 0-281% +1½ -115FanDuel | |||||||
 San Francisco 2-047% -2½ -110BetRivers | |||||||
 N.Y. Giants 0-279% +6½ -110BetMGM | |||||||
 Baltimore 1-129% -4½ -110Caesars | |||||||
 Buffalo 3-031 -11 -110Bet365 |
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