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Get ready for a thrilling NFL matchup as the Tennessee Titans take on the Arizona Cardinals on October 5, 2025, at State Farm Stadium in Glendale, AZ. The Cardinals, led by quarterback Kyler Murray, aim to capitalize on their home advantage, while the Titans, with Cam Ward at the helm, are eager to improve their record. The game will be broadcasted on CBS, offering fans a chance to witness the action live.
Both teams have struggled recently, with the Cardinals having a 2-2-0 record against the spread, and the Titans at 1-3-0. Arizona's defensive stats show a strong pass defense, allowing an average of 255.5 passing yards per game, while Tennessee's offensive line has been shaky, allowing 4.25 sacks per game. The Cardinals' pass offense, however, has been inconsistent, with Kyler Murray averaging 164.75 passing yards per game.
The point spread favors the Cardinals at -7.5, with an over/under total of 41 points. This suggests a low-scoring game, emphasizing the importance of strong defensive play. Betting trends indicate that Arizona's home-field advantage and superior pass defense could be pivotal. Consider starting your OddsTrader Turbo subscription to make informed betting decisions. Start your OddsTrader Turbo subscription now and place your bet with a U.S. regulated sportsbook.
In their last matchup on August 27, 2022, the Titans edged past the Cardinals with a 26-23 victory. The Cardinals are determined to even the score in this upcoming clash.
Cleveland 1-363% +3½ -110BetMGM | |||||||
Carolina 1-363% +1½ -110BetRivers | |||||||
![]() N.Y. Jets 0-477% +1½ -105FanDuel | |||||||
![]() Indianapolis 3-131% -7 -110FanDuel | |||||||
Philadelphia 4-033% -4 -110Caesars | |||||||
New Orleans 0-449% -1½ -110BetMGM | |||||||
![]() Baltimore 1-333% +2 -120BetMGM | |||||||
Arizona 2-232% -7½ -109BetRivers | |||||||
Seattle 3-165% -3½ -110Caesars | |||||||
![]() Cincinnati 2-284% +10½ -114BetRivers | |||||||
![]() L.A. Chargers 3-142% -2½ -120FanDuel | |||||||
Buffalo 4-022% -8 -105Caesars | |||||||
Jacksonville 3-183% +3½ -115Caesars | |||||||
![]() L.A. Rams 3-223 -7½ -115FanDuel |
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