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The Las Vegas Raiders are set to face off against the Indianapolis Colts on October 5, 2025, in what promises to be an exciting NFL matchup at Lucas Oil Stadium in Indianapolis, IN. As we approach Week 5, both teams are looking to capitalize on their strengths and address their weaknesses to secure a win. The Colts, led by quarterback Daniel Jones, have shown a strong passing offense, averaging 261 passing yards per game. However, their defense has been vulnerable, allowing an average of 223.75 passing yards per game.
On the other hand, the Raiders, with quarterback Geno Smith at the helm, have struggled defensively, giving up an average of 228.25 passing yards per game. Their offense, however, has been slightly more effective, with an average of 215.25 passing yards per game. The key to this game will likely be the performance of the quarterbacks and the ability of each team's defense to contain the opposing offense.
With the Colts being favored by 7 points and the total points set at 48, bettors should consider the potential for a high-scoring game. The Colts' home advantage and recent form, including a strong showing against the Titans, make them a formidable opponent. The Raiders will need to tighten up their defense and rely on their offensive playmakers to keep the game competitive. Catch the action on FOX and explore more NFL betting trends and insights on our OddsTrader Turbo page
Cleveland 1-363% +3½ -110BetMGM | |||||||
Carolina 1-363% +1½ -110BetRivers | |||||||
![]() N.Y. Jets 0-477% +1½ -105FanDuel | |||||||
![]() Indianapolis 3-131% -7 -110FanDuel | |||||||
Philadelphia 4-033% -4 -110Caesars | |||||||
New Orleans 0-449% -1½ -110BetMGM | |||||||
![]() Baltimore 1-334% +2 -120BetMGM | |||||||
Arizona 2-232% -7½ -109BetRivers | |||||||
Seattle 3-165% -3½ -110Caesars | |||||||
![]() Cincinnati 2-284% +10½ -114BetRivers | |||||||
![]() L.A. Chargers 3-142% -2½ -120FanDuel | |||||||
Buffalo 4-022% -8 -105Caesars | |||||||
Jacksonville 3-183% +3½ -115Caesars | |||||||
![]() L.A. Rams 3-223 -7½ -115FanDuel |
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