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The upcoming NFL showdown on January 17, 2026, features the Buffalo Bills visiting the Denver Broncos at Empower Field at Mile High in Denver, Colorado. This Saturday football game promises to be a thrilling contest broadcast on CBS, perfect for bettors looking to capitalize on expert insights and solid picks.
Our picks for the Buffalo Bills vs Denver Broncos game highlight a confident prediction of a 27-20 victory for the Broncos, with the moneyline favoring Denver. This prediction is backed by our recent betting tips and analysis, which have shown a strong hit rate and positive expected value (EV) in similar matchups, particularly in the moneyline market where we've enjoyed a 60% cover rate over the last 10 games. These stats empower bettors to make smart, informed decisions.
Empower Field at Mile High in Denver offers a classic outdoor venue atmosphere that often influences game dynamics, especially in January. The Broncos have demonstrated strong home-field performance, which aligns well with our picks and betting strategies for this game. For more comprehensive insights and to explore additional NFL picks, be sure to visit our NFL picks and predictions page.
Whether you're considering straight bets, parlays, or other betting options, our analysis provides valuable information to enhance your betting experience. Don't miss this exciting NFL event on January 17, 2026, and take advantage of the best betting opportunities available at top U.S. sportsbooks.
Denver 14-369% +1½ -115Bovada | |||||||
Seattle 14-351% -7½ -103Heritage | |||||||
New England 15-3100% -2½ -120BetOnline | |||||||
![]() Chicago 12-675% +4½ -108Heritage |