Jan 11, 2026 1:00 PM EST

Wild Card

Buffalo

13-4

Jacksonville

BUF

-1 (-105)o52½ (-110)

CBS

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Buffalo Bills vs Jacksonville Jaguars Odds

Updated:Jan 7, 2026 1:17 AM EST

The NFL clash between the Buffalo Bills and Jacksonville Jaguars is set for January 11, 2026, at EverBank Stadium in Jacksonville, FL. This game kicks off the 2025-26 NFL season and promises to be an exciting Sunday football event broadcasted on CBS. Bettors will want to pay close attention to the odds and betting lines as they prepare to wager on this matchup.

Currently, the Buffalo Bills are favored with a point spread of -1 -107, while the Jaguars hold a +1 -113 spread. The opening odds have seen a slight adjustment favoring the Bills, which may indicate growing confidence in their performance. The total points line is set at 52.5 with the under at -112, suggesting a potentially tight defensive game.

Understanding these odds and how they have shifted is crucial for making smart betting decisions. The Bills, with their strong home advantage at EverBank Stadium, are expected to leverage their experience, but the Jaguars cannot be underestimated. Bettors should explore the latest NFL odds to spot value and trends. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

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Personalize your notifications and get updates on the teams, players or events you care about most. SAT 01/104:30 PM L.A. Rams 12-5 28% -10 -117BetRivers
Carolina 8-9 72% +10½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 01/108:00 PM Green Bay 9-7-1 67% PK -114BetRivers
Chicago 11-6 33% +1½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/111:00 PM Buffalo 12-5 65% PK -114BetRivers
Jacksonville 13-4 35% +1½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/114:30 PM San Francisco 12-5 46% +4½ -110Caesars
Philadelphia 11-6 54% -4½ -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 01/118:00 PM L.A. Chargers 11-6 74% +3½ -109Caesars
New England 14-3 26% -3½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. MON 01/128:00 PM Houston 12-5 41% -3 -112Caesars
Pittsburgh 10-7 59% +3½ -120SugarHouse

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