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The upcoming NFL showdown between the Chicago Bears and San Francisco 49ers on December 28, 2025, promises to be an electrifying Sunday night football event at Levi's Stadium in Santa Clara, CA. As the Bears visit the 49ers for Week 17, bettors are eager for expert picks and betting tips to make informed wagers.
Our prediction model favors a close game with the 49ers narrowly winning 26-24, suggesting a tight battle with a spread leaning slightly towards Chicago +3 for value bettors. The total points are expected to be just under 51.5, a market where our model has shown a strong hit rate and positive EV in recent games.
In the last 10 games, our predictions focusing on the American Total market have been particularly profitable, winning over half the time with a high expected value. This insight is crucial for bettors looking to capitalize on the under 51.5 total points bet for this matchup. The game will be broadcast on NBC and Peacock, offering fans and bettors a great viewing experience.
For those looking to dive deeper into NFL betting, check out our comprehensive NFL picks and predictions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Washington 4-1160% +7 -120BetRivers | |||||||
Minnesota 7-866% +6 -110Bet365 | |||||||
![]() Kansas City 6-973% +13 -110Bet365 | |||||||
![]() L.A. Chargers 11-448% -1½ -112BetRivers | |||||||
Green Bay 9-5-142% -2½ -105FanDuel | |||||||
![]() Cincinnati 5-1011% -7 -108BetRivers | |||||||
Carolina 8-764% +7½ -120FanDuel | |||||||
Cleveland 3-1282% +4 -108BetRivers | |||||||
![]() Tennessee 3-1265% +3 -118FanDuel | |||||||
Miami 6-994% +5½ -110Bet365 | |||||||
![]() Indianapolis 8-7- +6½ -104FanDuel | |||||||
![]() N.Y. Jets 3-12100% +13½ -110Bet365 | |||||||
![]() Las Vegas 2-1350% -1 -105BetMGM | |||||||
Buffalo 11-433% -2 -112Caesars | |||||||
![]() San Francisco 11-4100% -2½ -120BetRivers | |||||||
![]() Atlanta 6-987% +8½ -115Caesars |
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