Tampa Bay Buccaneers vs Detroit Lions Picks

On October 20, 2025, prime-time Monday night football shines bright as the Tampa Bay Buccaneers vs Detroit Lions face off at Ford Field in Detroit, MI. The Buccaneers arrive after a hard-fought road victory, while the Lions defend home turf in a crucial NFC showdown. Kickoff airs on ABC/ESPN, setting the stage for a high-stakes REG Week 7 thriller.

The NFL picks model forecasts a tight battle, projecting Detroit to score 26 points and Tampa Bay 25. However, our predictions data highlights value on the Buccaneers +4.5 spread, identifying favorable lines where bettors can capitalize on key matchups and situational trends. Expect a back-and-forth affair with defensive adjustments playing a big role down the stretch.

Our analytical framework has excelled, going 7–3 on 2-way moneyline calls over the last 10 games, translating into consistent EV gains for subscribers. The point-spread market for Tampa Bay +4.5 boasts a 56.4% hit rate and 5.4% EV, making it the top wager for this contest. These actionable insights empower bettors to make informed decisions backed by data-driven rigor.

Want more angles and alternative bets? Explore deeper breakdowns on the NFL picks page and uncover additional edge plays. Ready to elevate your game with real-time odds and advanced analytics? Start an OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook to benefit from the proven model beating the market.