Jacksonville Jaguars vs Tennessee Titans Betting Trends

The upcoming NFL Week 13 matchup on November 30, 2025, features the Jacksonville Jaguars visiting the Tennessee Titans at Nissan Stadium in Nashville, TN. This Sunday football game promises to deliver exciting betting trends and game insights for fans and bettors alike. Jacksonville enters this game as the favorite with a -6 point spread, while the total points line is set at 41.5, favoring the over.

Jacksonville's offense, led by starting quarterback Trevor Lawrence, has been strong this season, averaging 330.9 total yards per game with a balanced attack of 202.8 passing yards and 128.1 rushing yards. The Jaguars face a tough Tennessee defense that allows 352.5 total yards per game, with a pass defense that gives up 219.7 yards and run defense allowing 132.8 yards. Tennessee's offense, under quarterback Cam Ward, averages 247.4 total yards, with 169.8 passing yards and 77.5 rushing yards, against a Jacksonville defense allowing 323.8 total yards per game.

Injuries could play a role, as Jacksonville is missing key offensive lineman Patrick Mekari and defensive end Travon Walker, while Tennessee has several questionable players including wide receiver Elic Ayomanor and tight end Chig Okonkwo, both expected to play. Tennessee's run offense vs Jacksonville's run defense and Jacksonville's pass protection against Tennessee's pass rush will be critical matchups to watch.

The Jaguars have a solid 7-4 straight-up record and 6-5 against the spread, while the Titans struggle with a 1-10 straight-up and 5-6 ATS record. The best odds currently favor Jacksonville at -290 moneyline and -6 point spread, making them a strong best bet for this game. The game will be broadcast on CBS, providing great visibility for Sunday football fans.

For bettors looking to capitalize on these betting trends and game insights, this matchup offers a compelling opportunity. Jacksonville's balanced offense and strong ATS record make them a smart pick against the spread. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. Also, check out their last matchup on December 29, 2024, where Jacksonville won 20-13 for added perspective.